Monthly Archives: June 2011

Adaptation

Increased heart tolerance to hypoxia at high altitude

Prof. Gustavo Zubieta-Castillo performed isolated dog heart perfusion in order to study heart function at high altitude. He then observed that the hearts of high altitude residents were more tolerant to hypoxia than those at sea level, around 1961. This is considered one of the first observations with this concept. Ever since and gradually it has been further studied and applied practically with distinguished colleagues such as Dr. Emilio Marticorena from Peru that showed that high altitude cardiac rehabilitation is faster at high altitude. Frantisek Kolar from the Czech Academy of Sciences Institute, has performed extraordinary advance in research of hearts in rats exposed to hypoxia, further advancing in this concept. We have heard that Alberto Hurtado from Peru had similar ideas. Here is the Newspaper “Ultima Hora” publication back in 1964:

 

 

Medical news

Scientific articles ranking in high altitude domain

ranked scientific articles this way:
Wednesday, June 1 , 2011

List 2: Top 10 Articles Published in the Same Domain Since Your Publication

Zubieta-Calleja GR, Paulev PE, Zubieta-Calleja L, Zubieta-Calleja N, Zubieta-Castillo G: Hypoventilation in chronic mountain sickness: a mechanism to preserve energy. J Physiol Pharmacol; 2006 Sep;57 Suppl 4:425-30

Go to the article

León-Velarde F, Villafuerte FC, Richalet JP: Chronic mountain sickness and the heart. Prog Cardiovasc Dis; 2010 May-Jun;52(6):540-9
Go to the article

Moore LG, Niermeyer S, Vargas E: Does chronic mountain sickness (CMS) have perinatal origins? Respir Physiol Neurobiol; 2007 Sep 30;158(2-3):180-9
Go to the article

Rivera-Ch M, Huicho L, Bouchet P, Richalet JP, León-Velarde F: Effect of acetazolamide on ventilatory response in subjects with chronic mountain sickness. Respir Physiol Neurobiol; 2008 Aug 31;162(3):184-9
Go to the article

Jafarian S, Gorouhi F, Ghergherechi M, Lotfi J: Respiratory rate within the first hour of ascent predicts subsequent acute mountain sickness severity. Arch Iran Med; 2008 Mar;11(2):152-6
Go to the article

Zubieta-Castillo G Sr, Zubieta-Calleja GR Jr, Zubieta-Calleja L: Chronic mountain sickness: the reaction of physical disorders to chronic hypoxia. J Physiol Pharmacol; 2006 Sep;57 Suppl 4:431-42
Go to the article

Maignan M, Rivera-Ch M, Privat C, León-Velarde F, Richalet JP, Pham I: Pulmonary pressure and cardiac function in chronic mountain sickness patients. Chest; 2009 Feb;135(2):499-504
Go to the article

Penaloza D, Arias-Stella J: The heart and pulmonary circulation at high altitudes: healthy highlanders and chronic mountain sickness. Circulation; 2007 Mar 6;115(9):1132-46
Go to the article

Yan JH, Li ZQ, Ji LH, Chai KX, Ge RL: [Changes of serum angiogenesis in patients with chronic mountain sickness]. Zhongguo Ying Yong Sheng Li Xue Za Zhi; 2009 Nov;25(4):457-60
Go to the article

Huicho L, Xing G, Qualls C, Rivera-Ch M, Gamboa JL, Verma A, Appenzeller O: Abnormal energy regulation in early life: childhood gene expression may predict subsequent chronic mountain sickness. BMC Pediatr; 2008;8:47
Go to the article

Read more »
Back to top^

List 3: Top 10 Articles Published in the Same Domain, All Time

Zubieta-Calleja GR, Paulev PE, Zubieta-Calleja L, Zubieta-Calleja N, Zubieta-Castillo G: Hypoventilation in chronic mountain sickness: a mechanism to preserve energy. J Physiol Pharmacol; 2006 Sep;57 Suppl 4:425-30
Go to the article

Sun S, Oliver-Pickett C, Ping Y, Micco AJ, Droma T, Zamudio S, Zhuang J, Huang SY, McCullough RG, Cymerman A, Moore LG: Breathing and brain blood flow during sleep in patients with chronic mountain sickness. J Appl Physiol; 1996 Aug;81(2):611-8
Go to the article

Sun SF, Huang SY, Zhang JG, Droma TS, Banden G, McCullough RE, McCullough RG, Cymerman A, Reeves JT, Moore LG: Decreased ventilation and hypoxic ventilatory responsiveness are not reversed by naloxone in Lhasa residents with chronic mountain sickness. Am Rev Respir Dis; 1990 Dec;142(6 Pt 1):1294-300
Go to the article

Erba P, Anastasi S, Senn O, Maggiorirni M, Bloch KE: Acute mountain sickness is related to nocturnal hypoxemia but not to hypoventilation. Eur Respir J; 2004 Aug;24(2):303-8
Go to the article

Richalet JP, Rivera M, Bouchet P, Chirinos E, Onnen I, Petitjean O, Bienvenu A, Lasne F, Moutereau S, León-Velarde F: Acetazolamide: a treatment for chronic mountain sickness. Am J Respir Crit Care Med; 2005 Dec 1;172(11):1427-33
Go to the article

León-Velarde F, Arregui A, Vargas M, Huicho L, Acosta R: Chronic mountain sickness and chronic lower respiratory tract disorders. Chest; 1994 Jul;106(1):151-5
Go to the article

León-Velarde F, Villafuerte FC, Richalet JP: Chronic mountain sickness and the heart. Prog Cardiovasc Dis; 2010 May-Jun;52(6):540-9
Go to the article

Moore LG, Niermeyer S, Vargas E: Does chronic mountain sickness (CMS) have perinatal origins? Respir Physiol Neurobiol; 2007 Sep 30;158(2-3):180-9
Go to the article

Ge RL, Shai HR, Takeoka M, Hanaoka M, Koizumi T, Matsuzawa Y, Kubo K, Kobayashi T: Atrial natriuretic peptide and red cell 2,3-diphosphoglycerate in patients with chronic mountain sickness. Wilderness Environ Med; 2001;12(1):2-7
Go to the article

Rivera-Ch M, Huicho L, Bouchet P, Richalet JP, León-Velarde F: Effect of acetazolamide on ventilatory response in subjects with chronic mountain sickness. Respir Physiol Neurobiol; 2008 Aug 31;162(3):184-9
Go to the article

Read more »
Back to top^

List 4: Top 10 Articles, with Free Full-Texts, Published in the Same Domain Since Your Publication

Zubieta-Calleja GR, Paulev PE, Zubieta-Calleja L, Zubieta-Calleja N, Zubieta-Castillo G: Hypoventilation in chronic mountain sickness: a mechanism to preserve energy. J Physiol Pharmacol; 2006 Sep;57 Suppl 4:425-30
Go to the article

Jafarian S, Gorouhi F, Ghergherechi M, Lotfi J: Respiratory rate within the first hour of ascent predicts subsequent acute mountain sickness severity. Arch Iran Med; 2008 Mar;11(2):152-6
Go to the article

Zubieta-Castillo G Sr, Zubieta-Calleja GR Jr, Zubieta-Calleja L: Chronic mountain sickness: the reaction of physical disorders to chronic hypoxia. J Physiol Pharmacol; 2006 Sep;57 Suppl 4:431-42
Go to the article

Maignan M, Rivera-Ch M, Privat C, León-Velarde F, Richalet JP, Pham I: Pulmonary pressure and cardiac function in chronic mountain sickness patients. Chest; 2009 Feb;135(2):499-504
Go to the article

Penaloza D, Arias-Stella J: The heart and pulmonary circulation at high altitudes: healthy highlanders and chronic mountain sickness. Circulation; 2007 Mar 6;115(9):1132-46
Go to the article

Huicho L, Xing G, Qualls C, Rivera-Ch M, Gamboa JL, Verma A, Appenzeller O: Abnormal energy regulation in early life: childhood gene expression may predict subsequent chronic mountain sickness. BMC Pediatr; 2008;8:47
Go to the article

Gonzales GF, Gasco M, Tapia V, Gonzales-Castañeda C: High serum testosterone levels are associated with excessive erythrocytosis of chronic mountain sickness in men. Am J Physiol Endocrinol Metab; 2009 Jun;296(6):E1319-25
Go to the article

Stuber T, Sartori C, Schwab M, Jayet PY, Rimoldi SF, Garcin S, Thalmann S, Spielvogel H, Salmòn CS, Villena M, Scherrer U, Allemann Y: Exaggerated pulmonary hypertension during mild exercise in chronic mountain sickness. Chest; 2010 Feb;137(2):388-92
Go to the article

Moore JP, Claydon VE, Norcliffe LJ, Rivera-Ch MC, Lèon-Velarde F, Appenzeller O, Hainsworth R: Carotid baroreflex regulation of vascular resistance in high-altitude Andean natives with and without chronic mountain sickness. Exp Physiol; 2006 Sep;91(5):907-13
Go to the article

Bailey DM, Evans KA, James PE, McEneny J, Young IS, Fall L, Gutowski M, Kewley E, McCord JM, Møller K, Ainslie PN: Altered free radical metabolism in acute mountain sickness: implications for dynamic cerebral autoregulation and blood-brain barrier function. J Physiol; 2009 Jan 15;587(Pt 1):73-85
Go to the article

BioMedLib
Webster Ellard
Article Delivery Services
www.BioMedLib.com
Email correspondence: custserv@bmlsearch.com
Meetings, Uncategorized

Chronic Hypoxia Symposium IV

Dear colleagues from around the world:

After 3 successful Chronic Hypoxia Symposiums held in La Paz, Bolivia, we are very proud to announce that the IV Chronic Hypoxia Symposium will be held in India under the direction of Prof. Thuppil Venkatesh.

Please stayed tunned for the preliminaries that will soon surface.

In the meantime, we want to thank all those that participated and attended our III Chronic Hypoxia Symposium held in La Paz in Oct 2010. Our President Larry Silver was able to find support from CISCO that transmitted via Webex to all the participants  live presentations from around the world.

Gustavo Zubieta-Calleja
Vice-President
International Society of Chronic Hypoxia