{"id":1183,"date":"2020-03-19T19:27:56","date_gmt":"2020-03-19T23:27:56","guid":{"rendered":"http:\/\/altitudeclinic.com\/blog\/?p=1183"},"modified":"2020-03-21T19:53:32","modified_gmt":"2020-03-21T23:53:32","slug":"covid-19-hydrochloroquine-prevention-strategy-for-medical-personnel","status":"publish","type":"post","link":"https:\/\/altitudeclinic.com\/blog\/2020\/03\/covid-19-hydrochloroquine-prevention-strategy-for-medical-personnel\/","title":{"rendered":"CoVid-19 Hydroxychloroquine urgency prevention strategy for Medical Personnel"},"content":{"rendered":"
\"from:<\/a>
from: https:\/\/www.keckmedicine.org\/coronavirus\/<\/figcaption><\/figure>\n

It has been observed by several groups that Hydroxychloroquine has some effectiveness in the treatment of severe CoVid-19 cases. In-vitro, it has been shown to inhibit the SARS-CoV-2 virus[1,2,3]. The American government has announced that Hydroxychloroquine will be approved by the FDA, ASAP today (March 19, 2020).<\/p>\n

We are aware that full studies have to be carried out but, there is no time.<\/p>\n

The hospitals are being overflowed, the intensive care units are insufficient, medical resources are running out, even in the first-world countries!\u00a0\u00a0People are losing their lives at an alarming rate and the crucial ones turn out to be those of the medical personnel, doctors, nurses, and all those working in the hospitals. The whole planet is shutting down. The world economy is suffering the consequences and above all, it is taking away thousands of human lives.<\/p>\n

When you board a plane, prior to departure, you are always told that if there is an emergency related to cabin decompression in-flight, one fundamental advice is:
\nIf you are with a child, please put on the oxygen mask yourself first before putting the child’s mask on. This is a fundamental life-saving procedure since if the loss of consciousness hits the mother or father first then, for certain, not only will the parents lose their lives but also the child.
\nIn a similar manner, if the doctors, nurses and medical personnel fall sick with the Coronavirus, then the patients will also succumb (thousands and maybe tens or hundreds of thousands).<\/p>\n

Due to the emergency situation that the whole planet is suffering and particularly the medical and paramedical personnel with this extreme Pandemia, it is essential to consider prevention strategies.<\/p>\n

Consequently, we suggest that all medical staff and support teams in hospitals consider start taking Hydroxychloroquine as a preventive strategy, once per week, while studies are being carried out. This is based on the effect of hydroxychloroquine taken to reduce malaria-risk significantly. It is not a perfect solution but it is what is available. The dosage, side-effects, contraindications are available from IAMAT[4]. The long term use of this drug in several other pathologies is well known and apparently well tolerated. We are aware of the criticism that can arise from this. However, today, this world is in a critical emergency situation and the Coronavirus is implacable, unmerciful, selfish and cruel. And we, as physicians from all around the world, have the obligation to help with innovative ideas born from our extensive experience.<\/p>\n

The recommended initial dose could be 2 tablets orally for a total of 300mg or 400mg depending on the pharmaceutical presentation STAT, to be repeated every week if no symptoms appear provided there are no contraindications. If SARS-CoV-2 symptoms appear, a full daily dose will probably need to be administered along with the other medication. We cannot wait for full statistically proven studies. Nevertheless, the dosage and methods of administration can be modified with time. What is undeniable is that time is running out !!<\/p>\n

The medical personnel should be prioritized. Particularly in a low resource country.<\/p>\n

It is highly probable that this emergency life-saving strategy that we propose be considered for immediate execution in all medical personnel treating CoVid-19 hospitals around the world !!!<\/p>\n

    \n
  1. \u00a0Yao X,\u00a0Ye F,\u00a0Zhang M,\u00a0Cui C,\u00a0Huang B,\u00a0Niu P,\u00a0Liu X,\u00a0Zhao L,\u00a0Dong E,\u00a0Song C,\u00a0Zhan S,\u00a0Lu R,\u00a0Li H,\u00a0Tan W,\u00a0Liu D. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)<\/a>.\u00a0Clin Infect Dis.<\/a>\u00a02020 Mar 9. pii: ciaa23<\/li>\n
  2. Jia Liu,\u00a0Ruiyuan Cao,\u00a0Mingyue Xu,\u00a0Xi Wang,\u00a0Huanyu Zhang,\u00a0Hengrui Hu,\u00a0Yufeng Li,\u00a0Zhihong Hu,\u00a0Wu Zhong\u00a0&\u00a0Manli Wang.\u00a0 Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro.<\/a>\u00a0Cell Discovery<\/i>\u00a0volume<\/span>\u00a06<\/b>, Article\u00a0number:\u00a016<\/span>\u00a0(2020<\/span>)<\/li>\n
  3. Devaux CA,\u00a0Rolain JM,\u00a0Colson P,\u00a0Raoult D.\u00a0 New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?<\/a>\u00a0Int J Antimicrob Agents.\u00a02020 Mar 11:105938<\/li>\n
  4. IAMAT<\/a>. How to protect yourself against Malaria. 2019.<\/li>\n<\/ol>\n

    Other ideas have previously been expressed\u00a0on March 17, 2020, in relation to the original ideas on Jan 30, 2020. Click here to read them<\/a>.<\/p>\n

    Prof. Dr. Gustavo Zubieta-Calleja
    \nDr. Natalia Zubieta-Calleja
    \n    High Altitude Pulmonary and Pathology Institute (IPPA)<\/a><\/h6>\n

    La Paz, Bolivia<\/p>\n

    March 19, 2020<\/p>\n

    ___________________________________________________________________________<\/p>\n

    Espa\u00f1ol<\/strong><\/p>\n

    ESTRATEGIA URGENTE PREVENTIVA CON HIDROXICLOROQUINA PARA EL PERSONAL MEDICO ANTE EL COVID-19.<\/h2>\n

    <\/h1>\n

     <\/p>\n

    \"from:<\/a>
    from: https:\/\/www.keckmedicine.org\/coronavirus\/<\/figcaption><\/figure>\n

    Queridos colegas:<\/p>\n

    Varios grupos han observado que la Hidroxicloroquina tiene cierta efectividad en el tratamiento de casos graves de CoVid-19. In vitro, se ha demostrado que inhibe el virus SARS-CoV-2 [1, 2, 3]. Hoy, 19 de Marzo de 2020, el gobierno estadounidense ha anunciado que la hidroxicloroquina ser\u00e1 aprobada por la FDA lo antes posible.<\/p>\n

    Somos conscientes de que se deben realizar estudios completos, pero no hay tiempo.<\/p>\n

    Los hospitales se est\u00e1n desbordando, las unidades de cuidados intensivos son insuficientes, los recursos m\u00e9dicos se est\u00e1n agotando, \u00a1incluso en los pa\u00edses del primer mundo! Las personas est\u00e1n perdiendo la vida a un ritmo alarmante y los que est\u00e1n sufriendo contagios de manera preocupante resultan ser el personal m\u00e9dico, para-m\u00e9dico, enfermeras y todos los que trabajan en los hospitales. Todo el planeta se est\u00e1 paralizando. La econom\u00eda mundial est\u00e1 sufriendo las consecuencias y sobre todo miles de vidas humanas se est\u00e1n perdiendo.<\/p>\n

    Cuando Ud. aborda un avi\u00f3n, antes del despegue, siempre le informan que si hay una descompresi\u00f3n de emergencia de la cabina en vuelo, un consejo fundamental es el siguiente:
    \nSi Ud. est\u00e1 con un ni\u00f1o, p\u00f3ngase primero la m\u00e1scara de ox\u00edgeno antes de ponersela al\/la ni\u00f1o\/a. Este procedimiento es fundamental para salvar vidas, ya que si la p\u00e9rdida de conciencia golpea primero a la madre o al padre, entonces, con certeza, no solo perder\u00e1n ellos la vida sino tambi\u00e9n el\/la ni\u00f1o\/a.
    \nDe manera similar, si los m\u00e9dicos, las enfermeras y el personal m\u00e9dico se enferman con el coronavirus, los pacientes tambi\u00e9n sucumbir\u00e1n (miles y quiz\u00e1s decenas o cientos de miles).<\/p>\n

    Debido a la situaci\u00f3n de emergencia que sufre todo el planeta y, en particular, el personal m\u00e9dico y param\u00e9dico de esta pandemia extrema, es esencial considerar estrategias de prevenci\u00f3n.<\/p>\n

    En consecuencia, sugerimos que todo el personal m\u00e9dico y los equipos de apoyo en los hospitales consideren comenzar a tomar hidroxicloroquina como estrategia preventiva, una vez por semana,\u00a0 mientras se realizen estudios completos. Esto est\u00e1 basado en la metodolog\u00eda para reducir el riesgo de malaria significativamente. No es una soluci\u00f3n perfecta, pero es lo que est\u00e1 disponible. La dosis, los efectos secundarios y las contraindicaciones est\u00e1n disponibles en IAMAT [4]. Tratamientos prolongados para otras patolog\u00edas con este medicamento, aparentemente son bien tolerados. Somos conscientes de las cr\u00edticas que pueden surgir de esto. Sin embargo, hoy, este mundo se encuentra en una situaci\u00f3n cr\u00edtica de emergencia y el Coronavirus es implacable, despiadado, ego\u00edsta y cruel.<\/p>\n

    La dosis inicial recomendada podr\u00eda ser 2 tabletas de 300 mg por v\u00eda oral STAT, que se repetir\u00e1 cada semana si no aparecen los s\u00edntomas. siempre que no hayan contraindicaciones. Si aparecieran los s\u00edntomas de SARS-CoV-2, probablemente ser\u00e1 necesario administrar una dosis diaria completa junto con los otros medicamentos. No podemos esperar a estudios cient\u00edficos completos estad\u00edsticamente comprobados sin embargo, las dosis e indicaciones se podr\u00e1n mejorar a trav\u00e9s del tiempo. Lo irrefutable es que el tiempo se acaba …<\/p>\n

    Se debe priorizar al personal m\u00e9dico. El tiempo dir\u00e1 si esta estrategia deba expandirse a toda la poblaci\u00f3n.<\/p>\n

    \u00a1Es muy probable que esta estrategia de emergencia para salvar vidas que proponemos hoy, sea considerada para su ejecuci\u00f3n inmediata en todo el personal m\u00e9dico que trata el Co-Vid-19 en los hospitales de todo el mundo!<\/p>\n

     <\/p>\n

    Otras ideas fueron expresadas\u00a0<\/a>el 30 de Enero de 2020 y luego modificados el 17 de Marzo 2020. Para leerlas haga click aqui<\/a>.<\/p>\n

    Prof. Dr. Gustavo Zubieta-Calleja
    \nDr. Natalia Zubieta-Calleja
    \n    High Altitude Pulmonary and Pathology Institute (IPPA)<\/a><\/p>\n

    La Paz, Bolivia<\/p>\n

    March 19, 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

    It has been observed by several groups that Hydroxychloroquine has some effectiveness in the treatment of severe CoVid-19 cases. In-vitro, it has been shown to inhibit the SARS-CoV-2 virus[1,2,3]. The American government has announced that Hydroxychloroquine will be approved by the FDA, ASAP today (March 19, 2020). We are aware that full studies have to … Continue reading CoVid-19 Hydroxychloroquine urgency prevention strategy for Medical Personnel<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":1192,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,3],"tags":[],"class_list":["post-1183","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-featured","category-medical-news"],"_links":{"self":[{"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/posts\/1183","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/comments?post=1183"}],"version-history":[{"count":36,"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/posts\/1183\/revisions"}],"predecessor-version":[{"id":1197,"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/posts\/1183\/revisions\/1197"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/media\/1192"}],"wp:attachment":[{"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/media?parent=1183"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/categories?post=1183"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/altitudeclinic.com\/blog\/wp-json\/wp\/v2\/tags?post=1183"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}