ranked scientific articles this way:

Wednesday, June 1 , 2011

List 2: Top 10 Articles Published in the Same Domain Since Your Publication Zubieta-Calleja GR, Paulev PE, Zubieta-Calleja L, Zubieta-Calleja N, Zubieta-Castillo G: Hypoventilation in chronic mountain sickness: a mechanism to preserve energy. J Physiol Pharmacol; 2006 Sep;57 Suppl 4:425-30 Go to the article León-Velarde F, Villafuerte FC, Richalet JP: Chronic mountain sickness and the heart. Prog Cardiovasc Dis; 2010 May-Jun;52(6):540-9 Go to the article Moore LG, Niermeyer S, Vargas E: Does chronic mountain sickness (CMS) have perinatal origins? Respir Physiol Neurobiol; 2007 Sep 30;158(2-3):180-9 Go to the article Rivera-Ch M, Huicho L, Bouchet P, Richalet JP, León-Velarde F: Effect of acetazolamide on ventilatory response in subjects with chronic mountain sickness. Respir Physiol Neurobiol; 2008 Aug 31;162(3):184-9 Go to the article Jafarian S, Gorouhi F, Ghergherechi M, Lotfi J: Respiratory rate within the first hour of ascent predicts subsequent acute mountain sickness severity. Arch Iran Med; 2008 Mar;11(2):152-6 Go to the article Zubieta-Castillo G Sr, Zubieta-Calleja GR Jr, Zubieta-Calleja L: Chronic mountain sickness: the reaction of physical disorders to chronic hypoxia. J Physiol Pharmacol; 2006 Sep;57 Suppl 4:431-42 Go to the article Maignan M, Rivera-Ch M, Privat C, León-Velarde F, Richalet JP, Pham I: Pulmonary pressure and cardiac function in chronic mountain sickness patients. Chest; 2009 Feb;135(2):499-504 Go to the article Penaloza D, Arias-Stella J: The heart and pulmonary circulation at high altitudes: healthy highlanders and chronic mountain sickness. Circulation; 2007 Mar 6;115(9):1132-46 Go to the article Yan JH, Li ZQ, Ji LH, Chai KX, Ge RL: [Changes of serum angiogenesis in patients with chronic mountain sickness]. Zhongguo Ying Yong Sheng Li Xue Za Zhi; 2009 Nov;25(4):457-60 Go to the article Huicho L, Xing G, Qualls C, Rivera-Ch M, Gamboa JL, Verma A, Appenzeller O: Abnormal energy regulation in early life: childhood gene expression may predict subsequent chronic mountain sickness. BMC Pediatr; 2008;8:47 Go to the article Read more » Back to top^ List 3: Top 10 Articles Published in the Same Domain, All Time Zubieta-Calleja GR, Paulev PE, Zubieta-Calleja L, Zubieta-Calleja N, Zubieta-Castillo G: Hypoventilation in chronic mountain sickness: a mechanism to preserve energy. J Physiol Pharmacol; 2006 Sep;57 Suppl 4:425-30 Go to the article Sun S, Oliver-Pickett C, Ping Y, Micco AJ, Droma T, Zamudio S, Zhuang J, Huang SY, McCullough RG, Cymerman A, Moore LG: Breathing and brain blood flow during sleep in patients with chronic mountain sickness. J Appl Physiol; 1996 Aug;81(2):611-8 Go to the article Sun SF, Huang SY, Zhang JG, Droma TS, Banden G, McCullough RE, McCullough RG, Cymerman A, Reeves JT, Moore LG: Decreased ventilation and hypoxic ventilatory responsiveness are not reversed by naloxone in Lhasa residents with chronic mountain sickness. Am Rev Respir Dis; 1990 Dec;142(6 Pt 1):1294-300 Go to the article Erba P, Anastasi S, Senn O, Maggiorirni M, Bloch KE: Acute mountain sickness is related to nocturnal hypoxemia but not to hypoventilation. Eur Respir J; 2004 Aug;24(2):303-8 Go to the article Richalet JP, Rivera M, Bouchet P, Chirinos E, Onnen I, Petitjean O, Bienvenu A, Lasne F, Moutereau S, León-Velarde F: Acetazolamide: a treatment for chronic mountain sickness. Am J Respir Crit Care Med; 2005 Dec 1;172(11):1427-33 Go to the article León-Velarde F, Arregui A, Vargas M, Huicho L, Acosta R: Chronic mountain sickness and chronic lower respiratory tract disorders. Chest; 1994 Jul;106(1):151-5 Go to the article León-Velarde F, Villafuerte FC, Richalet JP: Chronic mountain sickness and the heart. Prog Cardiovasc Dis; 2010 May-Jun;52(6):540-9 Go to the article Moore LG, Niermeyer S, Vargas E: Does chronic mountain sickness (CMS) have perinatal origins? Respir Physiol Neurobiol; 2007 Sep 30;158(2-3):180-9 Go to the article Ge RL, Shai HR, Takeoka M, Hanaoka M, Koizumi T, Matsuzawa Y, Kubo K, Kobayashi T: Atrial natriuretic peptide and red cell 2,3-diphosphoglycerate in patients with chronic mountain sickness. Wilderness Environ Med; 2001;12(1):2-7 Go to the article Rivera-Ch M, Huicho L, Bouchet P, Richalet JP, León-Velarde F: Effect of acetazolamide on ventilatory response in subjects with chronic mountain sickness. Respir Physiol Neurobiol; 2008 Aug 31;162(3):184-9 Go to the article Read more » Back to top^ List 4: Top 10 Articles, with Free Full-Texts, Published in the Same Domain Since Your Publication Zubieta-Calleja GR, Paulev PE, Zubieta-Calleja L, Zubieta-Calleja N, Zubieta-Castillo G: Hypoventilation in chronic mountain sickness: a mechanism to preserve energy. J Physiol Pharmacol; 2006 Sep;57 Suppl 4:425-30 Go to the article Jafarian S, Gorouhi F, Ghergherechi M, Lotfi J: Respiratory rate within the first hour of ascent predicts subsequent acute mountain sickness severity. Arch Iran Med; 2008 Mar;11(2):152-6 Go to the article Zubieta-Castillo G Sr, Zubieta-Calleja GR Jr, Zubieta-Calleja L: Chronic mountain sickness: the reaction of physical disorders to chronic hypoxia. J Physiol Pharmacol; 2006 Sep;57 Suppl 4:431-42 Go to the article Maignan M, Rivera-Ch M, Privat C, León-Velarde F, Richalet JP, Pham I: Pulmonary pressure and cardiac function in chronic mountain sickness patients. Chest; 2009 Feb;135(2):499-504 Go to the article Penaloza D, Arias-Stella J: The heart and pulmonary circulation at high altitudes: healthy highlanders and chronic mountain sickness. Circulation; 2007 Mar 6;115(9):1132-46 Go to the article Huicho L, Xing G, Qualls C, Rivera-Ch M, Gamboa JL, Verma A, Appenzeller O: Abnormal energy regulation in early life: childhood gene expression may predict subsequent chronic mountain sickness. BMC Pediatr; 2008;8:47 Go to the article Gonzales GF, Gasco M, Tapia V, Gonzales-Castañeda C: High serum testosterone levels are associated with excessive erythrocytosis of chronic mountain sickness in men. Am J Physiol Endocrinol Metab; 2009 Jun;296(6):E1319-25 Go to the article Stuber T, Sartori C, Schwab M, Jayet PY, Rimoldi SF, Garcin S, Thalmann S, Spielvogel H, Salmòn CS, Villena M, Scherrer U, Allemann Y: Exaggerated pulmonary hypertension during mild exercise in chronic mountain sickness. Chest; 2010 Feb;137(2):388-92 Go to the article Moore JP, Claydon VE, Norcliffe LJ, Rivera-Ch MC, Lèon-Velarde F, Appenzeller O, Hainsworth R: Carotid baroreflex regulation of vascular resistance in high-altitude Andean natives with and without chronic mountain sickness. Exp Physiol; 2006 Sep;91(5):907-13 Go to the article Bailey DM, Evans KA, James PE, McEneny J, Young IS, Fall L, Gutowski M, Kewley E, McCord JM, Møller K, Ainslie PN: Altered free radical metabolism in acute mountain sickness: implications for dynamic cerebral autoregulation and blood-brain barrier function. J Physiol; 2009 Jan 15;587(Pt 1):73-85 Go to the article BioMedLib Webster Ellard Article Delivery Services www.BioMedLib.com Email correspondence: custserv@bmlsearch.com

]]> http://altitudeclinic.com/blog/2011/06/scientific-articles-ranking-in-high-altitude-domain/feed/ 0 http://altitudeclinic.com/blog/2010/01/the-mountain-guru/ http://altitudeclinic.com/blog/2010/01/the-mountain-guru/#comments Thu, 14 Jan 2010 17:12:24 +0000 admin http://altitudeclinic.com/blog/?p=77 Prof. Dr. Gustavo Zubieta-Castillo (Sr.) has received a most extraordinary distinction and honor in Bangalore, India at the St. John’s Medical College:

In response to an invitation by Prof. Thuppil Venkatesh to attend a meeting and present their recent scientific work, Prof. Dr. Gustavo Zubieta-Castillo (Sr) and Prof. Dr. Gustavo Zubieta-Calleja (Jr) travelled to Bangalore, India and on the way there stopped in Copenhagen, Denmark to visit and discuss scientific projects with Prof. Dr. Poul-Erik Paulev. Further news on this will follow soon.

Once in India, they were received by the most distinguished Shashidhara N. who became along with Prof. Thuppil Venkatesh their guides, and colleagues of profound phylosophical discussions during 10 days of a most memorable visit to incredible India.

Having arrived at the modern airport in Bangalore, they were then transported to Kochi, where the 36th National Conference of Clinical Biochemists was carried out Nov 5-8th, 2009 under the direction of Prof. D.M.Vasudevan. After their presentation both Zubietas were driven to Mysore to meet Prof. Virupasksha Hosur and visit the extraordinary Mysore Palace. Elephants, crocodiles and bird watching filled them with eco-nature and a profound understanding of the wisdom of the people from India.

Upon returning to Bangalore Prof. Zubieta-Castillo (Sr.) and Prof. Zubieta-Calleja (Jr.) were invited to give a talk at the St. John’s Medical College  (see the invitation on the left). Much to their surprise, Prof. Thuppil Venkatesh leaded in the presentation and introduced the Director of the St John’s National Academy of Health Sciences Dr. Lawrence D’Souza, along with very distinguished personalities of Bangalore.

Then upon the podium, starting with Dr. Lawrence D’Souza one by one the wicks of a large oil lamp, were lighted by each of the distinguished guests as a sign of friendship and cooperation (photo below).

Shown at left: Dr. Prem Pais (Dean of St. John’s Medical College), Mr. A.S. Sadashivaiah, Chairman Karnataka State Pollution, Prof. Dr. Zubieta-Castillo (Sr.), Dr. Lawrence D’Souza, Director St. John’s National Academy of Health Sciences, Prof. Dr. Zubieta-Calleja(Jr) Padmashree Mahadevappa, Former Chancellor UAS and Prof. Thuppil Venkatesh, NRCLPI. (All photos courtesy of the distinguished colleagues from India)

Immediately afterwards, Dr. Lawrence D’Souza presented Prof. Dr. Gustavo Zubieta-Castillo (Sr) in a special ceremony a turbant, flowers and a gold plated oil lamp.

The special honors, the turbant, flowers, a gold plated oil lamp bestowed upon Prof. Dr. Gustavo Zubieta-Castillo at St. John’s National Academy of Health Sciences in Bangalore, India, Nov 11, 2009.

Then the honoree gave a talk on “Patho-Physiology of Adaptation to Hypoxia and Prof. Zubieta-Calleja (Jr) on ” The Current Status of Millions of Highlanders”.

The photo below shows the resemblance of Prof. Zubieta-Castillo with the late and famous legendary Indian Engineer-Statesman: Sir. Mokshagundam Visvesvarayya, as expressed by many distinguished attendees.

With Prof. Thuppil Venkatesh, Principal Advisor Quality Council of India (QCI) &
National Referral Centre for Lead Poisoning in India (NRCLPI)
Professor- Department of Biochemistry & Biophysics
St. John’s Medical College

At a dinner in the Country Club in Bangalore, Prof. Venkatesh surrounded by very important people gave Prof. Zubieta-Castillo, the following distinction:

Furthermore, he was repeatedly mentioned as a candidate for the Nobel Price in Medicine for he has determined that Chronic Mountain Sickness is not a “Loss of Adaptation” but rather a consequence of pulmonary diseases with shunts that increase the number of red cells (polyerythrocythemia) thereby saving the life of thousands of high altitude residents that have been intoxicated with drugs like Phenylhidrazine with the wrong concept of destroying the “excessive” red blood cells. This drug damaged the liver cells producing jaundice and also the endothelium of all vessels in the system, and lesions to the kidneys. His theories of Adaptation to life at the hypoxic levels of Mt. Everest applying the high altitude adaptation  formula, following Ohm’s law, and the triple hypoxia syndrome were also mentioned.

They likewise were also honored by a visit to his excellency Governor Karnataka, H R Bhardwaj, at the Governor’s Palace in Bangalore,  below :

Shown here Shashidhara N, Gustavo Zubieta-Calleja (Jr), His excellency Governor of Karnataka H R Bhardwaj, Gustavo Zubieta-Castillo (Sr), Thuppil Venkatesh.

So those of different countries must be wondering but what is a Guru?

A guru (Sanskrit: गुरु) is one who is regarded as having great knowledge, wisdom and authority in a certain area, and who uses it to guide others (teacher). As a principle for the development of consciousness it leads the creation from unreality to reality, from the darkness of ignorance to the light of knowledge.

The syllable gu means shadows
The syllable ru, he who disperses them,
Because of the power to disperse darkness
the guru is thus named.

– Advayataraka Upanishad 14—18, verse 5

from Wikipedia

]]> http://altitudeclinic.com/blog/2010/01/the-mountain-guru/feed/ 6 http://altitudeclinic.com/blog/2009/08/human-adaptation-to-high-altitude-and-sea-level/ http://altitudeclinic.com/blog/2009/08/human-adaptation-to-high-altitude-and-sea-level/#comments Fri, 28 Aug 2009 16:56:00 +0000 admin http://altitudeclinic.com/blog/?p=24

The effect of High to Low Altitude Adaptation on the

Multifocal Electroretinogram.

Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Glostrup, Denmark
High Altitude Pathology Institute, La Paz, Bolivia; Department of Ophthalmology, Glostrup Hospital, University of Copenhagen, Glostrup, Denmark

PURPOSE. To examine variations in retinal electrophysiology assessed by multifocal electroretinogram (mfERG) during acclimatization of native highlanders during adaptation to normobaric normoxia at sea level. METHODS. Eight healthy residents of from the greater La Paz area in Bolivia (3600 m above sea level) were examined over 72 days after arriving in Copenhagen, Denmark (sea level). A control group of 8 healthy lowlanders was used for comparison. RESULTS. During the period of observation hemoglobin decreased from 16.7 gm/dL to 15.0 gm/dL (p = 0.0031), erythrocytes decreased from 5.3 T/l to 4.6 T/l (p = 0.0006), and hematocrit decreased from 49.4% to 42.2% (p = 0.0008). At baseline, Day 2 after arrival, the amplitudes (N1, P1, N2) of the mfERG were 43.1-59.9% higher in the highlanders than in lowlanders (p < 0.017). During acclimatization the mfERG amplitudes increased 16.9 to 20.4% (p < 0.028) to a level 73.2-87.0% higher in the highlanders than in lowlanders (p < 0.0008). The increase in amplitude was inversely proportional to the decrease in erythrocyte concentration (p = 0.023, 0.053, 0.12 for N1, P1, N2 respectively). CONCLUSIONS. Upon arrival at sea level, highlanders had markedly supernormal multifocal electroretinographic amplitudes that continued to increase during the 72 day period of observation where the highlanders’ hematocrit normalized. Our results suggest that acclimatization after a change in altitude and hence in ambient oxygen tension involves intrinsic retinal mechanisms and that acclimatization had not been completed at the end of the study.

Invest Ophthalmol Vis Sci. 2009 Feb 21.

extracted from:

http://www.ncbi.nlm.nih.gov/pubmed/19234353

Among them:

floating tennis courts,
marathon in space,
tennis heliport in Dubai,
mountain biking,
golf on snow,
tennis on top of water,
Ski in the dessert,
Cricket in the Himalayas,
tennis in a boat
and the football (soccer) game played on the summit of Mt. Sajama at 6542 m. that the High the Altitude Pathology Institute organized in August 2001.

Click here to view the photos.

Click here to read about the Sajama football game.

Dear colleagues and friends:

Thorsen HC, Zubieta-Calleja G, Paulev PE.

Paulev PE, Zubieta-Calleja GR.

Zubieta-Calleja GR, Paulev PE, Zubieta-Calleja L, Zubieta-Calleja N, Zubieta-Castillo G.

Zubieta-Castillo G Sr, Zubieta-Calleja GR Jr, Zubieta-Calleja L.