Conference of Prof. Dr. Gustavo Zubieta-Calleja at the lung division of the National Institutes of Health in Bethesda, Md.

Grand USA Chronic Hypoxia Tour 2018

Between April 18th and April 30th Prof. Dr. Gustavo Zubieta-Calleja, Director and Head of the High Altitude Pulmonary and Pathology Institute in La Paz, Bolivia, gave talks explaining the benefits of Life under Chronic Hypoxia (low-oxygen).

It started with a talk on April 18th at the National Institutes of Health, National Heart Heart, Lung and Blood Institute in Bethesda Maryland, in the Division of Lung Diseases. It’s director Dr. James  Kyley introduced Prof. Zubieta to a group of his top Staff scientists.

IMG_20180418_114148

The presentation was entitled: “Benefits of exposure to Chronic Hypoxia: Adaptation, Tolerance to Hypoxia, Acid-Base at high altitude and future space travel”. It was a stimulating talk that has a different concept regarding the traditional fears of hypoxia in Sea level physicians. This talk showed that chronic hypoxia at high altitude residents gives rise to many advantages, as a way of adaptation.

NIHConf3

Explaining exercise at high altitude

At the Lung division of the National Institutes of Health in Bethesda, Md. USA

At the Lung division of the National Institutes of Health in Bethesda, Md. USA

Among them he showed that Bolivians live longer at high altitude in the high altitude areas.

http://www.bldeujournalhs.in/article.asp?issn=2468-838X;year=2017;volume=2;issue=2;spage=80;epage=90;aulast=Zubieta-Calleja

This scientific paper is the most popular article in that journal thus far, since its publication on Dec 15, 2017. We have also been invited to write a book on this subject. So this is a transcendental paper in high altitude medicine.

Talking about 52 years of life at high altitude with a PaO2 of 60mmHg.

Talking about 52 years of life at high altitude with a PaO2 of 60mmHg.

However many other subjects were dealt with in the conference, like the Adaptation Formula that we developed.

Adaptation formula

And the Remarkable Tolerance to Hypoxia formula that we also created:

Screen Shot 2018-06-13 at 3.57.11 AM

This formula shows that paradoxically, the higher man goes to high altitude the more tolerance to hypoxia there is.  Compared to sea level, the high altitude residents of La Paz, are 1.7 times more tolerant to hypoxia. Similarly, on the summit of Mt. Everest, where humans have climbed to, without the assistance of oxygen, it is around 6 times. This outstanding capacity of survival in such low levels of oxygen is  proof that nature has wisely granted living beings the mechanisms to survive and sustain life even in the extreme environments.

From Left: Natalia Zubieta-DeUrioste, James Kyley, Director of the Lung division of the NIH and Gustavo Zubieta-Calleja (IPPA)

From Left: Natalia Zubieta-DeUrioste, James Kyley, Director of the Lung division of the NIH and Gustavo Zubieta-Calleja (IPPA).

Ricardo Balderrama, Prof. Dr. Gustavo Zubieta-Calleja and Jorge Ordenes, our distinguished guests at the talk.

Ricardo Balderrama, Prof. Dr. Gustavo Zubieta-Calleja and Jorge Ordenes, our distinguished guests at the talk.

Visiting the Afro-American Muesum in Washington. D.C. Rafaela, Natalia and Lucrecia DeUrioste.

Visiting the Afro-American Muesum in Washington. D.C. Rafaela, Natalia and Lucrecia DeUrioste.


We then moved on to meet Dr. Oscar Murillo, a distinguished Geriatrician in Pennsylvania.

In Dr. Oscar Murillo's home for the talk to the local Geriatrics Society in Penssylvania.

In Dr. Oscar Murillo’s home for the talk to the local Geriatrics Society in Penssylvania.

He kindly hosted a conference dinner at his beautiful residence in Schneksville, Penssylvania. The dinner was great. The members of the Geriatrics Society were a delight to share moments with.

Prof. Dr. Gustavo Zubieta-Calleja and Dr. Steven Fuller, Vice-President and Corporate Medical Director of the Presbyterian Senior Living.

Prof. Dr. Gustavo Zubieta-Calleja and Dr. Steven Fuller, Vice-President and Corporate Medical Director of the Presbyterian Senior Living.

Among them, Dr. Steven Fuller, a most distinguished Geriatrician with whom we shared many interesting comments regarding high altitude physiology.

Giving the talk to the Geriatric local society at Dr. Oscar Murillo's residence in Pennsyvania.

Giving the talk to the Geriatric local society at Dr. Oscar Murillo’s residence in Pennsyvania.

Dr. Oscar Murillo, Dr. Steven Fuller and the physicians and students of the Geriatric group.

Dr. Oscar Murillo, Dr. Steven Fuller and the physicians, nurses and students of the Geriatric group.

Dr. Oscar Murillo's Medical Consultation offices premises in Hannover, Pennsylvania.

Dr. Oscar Murillo’s Medical Consultation offices premises in Hannover, Pennsylvania.

Prof. Dr. Gustavo Zubieta-Calleja and Dr. Oscar Murillo, in the offices he constructed with two colleagues.

Prof. Dr. Gustavo Zubieta-Calleja and Dr. Oscar Murillo, in the offices he constructed with two colleagues.

Visiting the historic town of Gettysburg, thanks to Dr. Oscar Murillo and one of his colleagues.

Visiting the historic town of Gettysburg, thanks to Dr. Oscar Murillo and one of his colleagues.


Our next stop was Fayetteville, Ark where Prof. Zubieta-Calleja gave a talk at the Center for Space and Planetary  Sciences in the University of Arkansas.

At the university of Arkansas prior to the talk.

At the university of Arkansas prior to the talk.

He had attended this University during a year  as a Pre-med before his transfer to the Universidad Mayor de San Andres Medical School in La Paz, Bolivia. Prof. Dr. Gustavo Zubieta-Calleja, was an exchange student in Little Rock, Arkansas and lived with the Smith Family in 1973 prior to attending to the University of Arkansas.

Dinner at Mrs. Purcell Smith Jr's residence in Rogers. From Left: Mrs Purcell Smith Jr, Cindy Youngblood, Lucrecia DeUrioste, Rafaela Zubieta DeUrioste, Dr. Natalia Zubieta DeUrioste, Dr. Gustavo Zubieta-Calleja, Mr. Youngblood, Mrs. Youngblood.

Dinner at Mrs. Purcell Smith Jr’s residence in Rogers. From Left: Mrs Purcell Smith Jr, Cindy Youngblood, Lucrecia DeUrioste, Rafaela Zubieta DeUrioste, Dr. Natalia Zubieta DeUrioste, Dr. Gustavo Zubieta-Calleja, Mr.Jim Youngblood, Mrs. Dr. Katie Youngblood.

Mr. Jim Youngblood, working for NASA, had met and acquainted astronaut Ed White of the Apollo  program, who had given, as a Christmas present, an autographed photo to his son Tom Youngblood, currently a Pediatrician married to Cindy Smith. Astronaut Ed White was one of the three astronauts that unfortunately died in the tragic prelaunch burn of Apollo 1.  Such event initiated the sea level (760mmHg), in space cabin pressure flights with 21% oxygen.

Historic autographed photo of astronaut Ed. White given to Dr. Tom Youngblood, as a child.

Historic autographed photo of astronaut Ed. White given to Dr. Tom Youngblood, as a child.

This coincidence of meeting Mr. Jim Youngblood in the dinner prior to the talk on space travel, is truly extraordinary, since  for Prof Dr. Gustavo Zubieta-Calleja’s talk proposes that high altitude pressures (495mmHg) similar to the city of La Paz (3600m) be used in space capsules instead.

The title of the talk for the Center for Space and Planetary Sciences was about “Space travel under Chronic Hypoxia“.

Prof. Dr. Gustavo Zubieta-Calleja, explaining the logic behind his proposal for future space travel. Biology aiding Physics in the conquest of Space.

Prof. Dr. Gustavo Zubieta-Calleja, explaining the logic behind his proposal for future space travel. Biology aiding Physics in the conquest of Space.

The students's and staff of the Center for Planetary and Space Sciences at the University of Arkansas in Fayeteville, Ark.

The students’s and staff of the Center for Space and Planetary  Sciences at the University of Arkansas in Fayeteville, Ark.

It was in relation to  an original idea of Prof. Zubieta-Calleja back in 2007 as expressed in his book “Adaptation to High Altitude and to Sea Level: Acid-Base Equilibrium, Ventilation and Circulation in Chronic Hypoxia“.

Visiting the laboratory project on Titanus (one fo the moons of Jupiter) of PhD student Caitlin Ahrens at the Center for Space and Planetary Sciences.

Visiting the laboratory project on Titan (largest moon of Saturn) of PhD student Kendra Farnsworth at the Center for Space and Planetary Sciences, Univ of Arkansas. From Left. Larry Roe, Director, Kendra Farnsworth and Prof. Dr. Gustavo Zubieta-Calleja.,

Another image of the Titan Moon simulated environment project by student Kerna Farnsworth.

Another image of the Titan Moon simulation chamber by PhD student Kendra Farnsworth.

The idea is that future space travel has to be undertaken in high altitude environment similar to the city of  La Paz (3600m), within space capsules.

At the Arkansas Cneter for Spoace and Planetary Sciences. From Left: Cindy YOungblood, Dr. Gustavo Zubieta-Calleja and Dr. Tom Youngblood.

At the Arkansas Center for Space and Planetary Sciences. From Left: Cindy Youngblood, Dr. Gustavo Zubieta-Calleja and Dr. Tom Youngblood.

This would grant astronauts great advantages. It would allow for a practical solution to astronauts anemia in Space. Furthermore, it would give great advantages speeding up the possibility of going out of the space ship and using a space suit, since the pressure changes would not be as great. This would allow for much lighter space suits, aiding in the flexibility and maneuverability.

Entering the ARkansas Center for Sopace and Planetary Sciences. From Left Larry Roe, Director, Prof. Dr. Gustavo Zubieta-Calleja, Cindy Youngblood and Caitlin Ahrens pHd Student.

Entering the ARkansas Center for Sopace and Planetary Sciences. From Left Larry Roe, Director, Prof. Dr. Gustavo Zubieta-Calleja, Cindy Youngblood and Caitlin Ahrens pHd Student doing research on the cryo-geology and spectroscopy of PLUTO using the Pluto simulation Chamber..

Much more will come from this revolutionary concept, that will change forever the way humans travel in space. Please click below to see the BLDE Journal pre-print:

https://www.researchgate.net/publication/325536733_Space_travel_in_a_high_altitude_environment_One_more_step_in_human_BioSpaceFormin

All these ideas are born from over 48 years of experience in our Institute, founded by the late Prof. Dr. Gustavo Zubieta-Castillo:

The Mountain Guru


The final talk was given at Tulane Medical School in New Orleans, Louisiana.

Rafaela Zubieta, Prof. Dr. Gustavo Zubieta-Calleja, Dr. Natalia Zubieta-DeUrioste

Rafaela Zubieta, Prof. Dr. Gustavo Zubieta-Calleja, Dr. Natalia Zubieta-DeUrioste

This was a very special situation. On a previous conference talks organized by Prof. Thuppil Venkatesh in Dec 2017 throughout India, Prof. Zubieta-Calleja, had the opportunity to meet Prof. Dewan S.A. Mahid at Prof Kusal Das’ Laboratory in BLDE University in Vijayapur, India. Prof. Majid a most distinguished scientist of the Physiology Department at Tulane, invited Prof Zubieta-Calleja to go give a talk.

Tulane Conference invitation

Tulane Conference invitation

Prof. Zubieta-Calleja had been in New Orleans when he was 8 years old during two years because Prof. Dr. Gustavo Zubieta-Castillo was a visiting Professor at Tulane Medical School back in 1964.

We had a special bonus as we met our dear friend Prof. Rafael Rubio and Cherry his wife for the second time in beautiful New Orleans.

Prof. Dr. Gustavo Zubieta-Calleja with Prof. Rafael Rubio in New Orleans, LA.

Prof. Dr. Gustavo Zubieta-Calleja with Prof. Rafael Rubio in New Orleans, LA.

We had the most interesting discussions about science and likewise, Rafael and following the  extraordinary coincidences, Rafael had worked with Gustavo Zubieta-Castillo (Sr) in the 60’s at the Instituto de Cardiologia in Mexico. They had published a joint paper entitled “RUBIO, R., and-ZUBIETA, G.: ‘The variation of the electrical resistance of microelectrodes during the flow of current’, Acta Physiologica Latin Americana, 1961, 11. “, which became a very cited reference in physiology.

A special dinner was held at Prof. Edwan Mahid's residence in New Orleans. Top row from left: Prof. Zubieta-Calleja, Prof. Edwan Mahid, Daniel from Bangladesh. Prof. Rafael Rubio, Seated from left: Cherry Rubio, Rafaela Zubieta, Dr. Natalia Zubieta DeUrioste, NIna Mahid, Mrs. Daniel

A special dinner was held at Prof. Dewan Mahid’s residence in New Orleans.
Top row from left: Prof. Zubieta-Calleja, Prof. Edwan Mahid, Daniel from Bangladesh. Prof. Rafael Rubio, Seated from left: Cherry Rubio, Rafaela Zubieta, Dr. Natalia Zubieta DeUrioste, NIna Mahid, Mrs. Daniel

Dr. Rafael Rubio obtained his PhD in US and became a Professor of physiology at University of Virginia during over 30 years, becoming Emeritus. He now resides permanently in New Orleans and had written his book “Endothelial Luminal Membrane-Glycocalyx: Functionalities in Health and Disease” at Tulane.

At Prof. Gabriel Navar's office of Head of the Department of Physiology at Tulane Medical School in New Orleans, Louisiana

At Prof. Luis Gabriel Navar’s office os Chairman,  Department of Physiology and Director of the  Center for Biomedical Research Excellence in Hypertension and Renal Biology at Tulane Medical School in New Orleans, Louisiana. From left: Natalia Zubieta, Rafaela Zubieta, Prof. Dr. Gustavo Zubieta-Calleja, Prof. Luis Gabriel Navar. Prof. Dewan Mahid.

Prof. Dr. Gustavo Zubieta-Calleja's seminar at Tulane.

Prof. Dr. Gustavo Zubieta-Calleja’s seminar at Tulane.

Prof. Navar introducing the seminar to his staff and students at the physiology Department of Tulane in New Orleans, LA. USA

Prof. Navar introducing the seminar to his staff and students at the physiology Department of Tulane in New Orleans, LA. USA

The talk was carried out on April 30, 2018 at the Physiology Department which runs under the direction of Prof. Gabriel Navar. It was a pleasure to meet him and to discuss subjects of mutual interest.

Prof. Gabriel Navar, second from the left.

Prof. Gabriel Navar, second from the left.

He heads the Center for Biomedical Research Excellence in  Hypertension and Renal Biology and has a staff that is truly outstanding. The program of visits is below:

Tulane visit program

Tulane visit program

We truly enjoyed meeting such distinguished colleagues at Tulane, and particularly Dr.  Minolfa Prieto.

In this opportunity Prof. Dr. Gustavo Zubieta-Calleja was with his IPPA team, his brand new colleague and scientific researcher Dr. Natalia Zubieta, our language expert Rafaela Zubieta and Lucrecia De Urioste our International Relations expert.

Dr. Oscar Murillo, Dr. Natalia Zubieta-DeUrioste, Rafaela Zubieta-DeUrioste, Lic. Lucrecia DeUrioste, visiting the Empire State.

Dr. Oscar Murillo, Dr. Natalia Zubieta-DeUrioste, Rafaela Zubieta-DeUrioste, Lic. Lucrecia DeUrioste, visiting St. Patricks in Manhattan..

 

Come join us at the  7th CHRONIC HYPOXIA SYMPOSIUM in Feb 2019 !!

IMG_20171214_144837

India conferences 2017

India 2017 Conferences

Nov 29 – Dec 15, 2017

Once again Prof. Dr. Gustavo Zubieta-Calleja was invited to participate in ACBICON (Association of Clinical Biochemists of India Conference, and to give talks at BLDE University between Nov 29 and Dec 15, 2017.  Prof. Thuppil Venkatesh, was the host and he organized several conferences and meetings along with some visits to temples and friends in Bangalore, Lucknow, and Vijayapur. Here is his description of the events.

The inauguration was carried out by Prof. M.L.B. Bhatt, Vice-Chancellor of the famous KING GEORGE’S UNIVERSITY in Lucknow. His speech was very interesting and full of oratory talent. He talked about “The Lead Man” referring to the famous Prof. Thuppil Venkatesh and added that also present was  “The Hypoxia Man” referring to me. I felt touched by such kind denomination. Many colleagues then started calling me “The Hypoxia Man” the rest of the meeting, which obviously makes it easier for them than to say my name that is complicated in India, as you may appreciate. They often confuse my First name Gustavo with my Last name Zubieta-Calleja. These are handicaps of cultural differences.

Acbicon times

Acbicon times

Opening ceremony of the ACBICON conference in Lucknow, India Dec 3 2017

Opening ceremony of the ACBICON conference in Lucknow, India Dec 3 2017

ACBICON opening ceremony speech by Prof. Dr. Gustavo Zubieta-Calleja

ACBICON opening ceremony speech by Prof. Dr. Gustavo Zubieta-Calleja

Lighting the Candles of Enlightment as the opening ceremony

Lighting the Candles of Enlightenment as the opening ceremony. Shown from the right The Vice-Chancellor of King George’s University Prof. M.L.B. Bhatt, Vice-Chancellor of Era University Prof. Abbas Ali, Mahdi the Head organizer and Prof. Rajiv Sighn Secretary of Organization.

IMG_20171206_071847

Prof. Abbas Ali Mahdi, the previous Head of the Biochemistry Department at King George’s University and now Vice- Chancellor of Era University, was the organizer of this interesting meeting in Lucknow.  There I had the opportunity of meeting once again Prof. Praveen Sharma, the Head of the Biochemistry of the All India Institute of Medical Sciences in Jodhpur and Chief Editor of the Indian Journal of Biochemistry. I was invited to participate in the editorial board of the Journal and had the privilege of attending the  yearly meeting.

My conference was entitled:

Clinical Biochemistry at the summit of Mt. Everest: Correct interpretation of arterial blood gases and acid-base status.

We then flew back to Bangalore where we met some old friends like Parthasarathy and Shashi.

We then travelled by train to Vijayapur and where we spent 4 days in multiple activities at the distinguished BLDE University Physiology Department that is more than 100 years old. We were greeted once more, by Prof. Kusal Das Head of the Laboratory of Vascular Physiology and Medicine 

Majid.Gustavo.PhD Talk.IQAC

Lecture series.

With Professor of Physiology Dewan Majid of Tulane Medical School, we shared very pleasant moments along with Prof. Thuppil Venkatesh and Parthasarathy.

Gustavo.Talk.MEDICAL

I gave a talk related to chronic hypoxia and how high altitude residents have achieved what we call an “advantage for survival” and where I explained that we observe that sea level residents have a very poor tolerance to hypoxia,  inducing us to affirm that they suffer a “disability”, whereby they have poor response to hypoxia and in contrast high altitude residents can even achieve extended longevity.

Incidentally, a researcher  wrote:

Ian Gavaraeb, Academic writer at Livingston Research

Ian Gavaraeb, Academic writer at Livingston Research

 

If any one else knows any high altitude cities in the world where there is extended longevity please let us know by sending us an email: zubieta@altitudeclinic.com

Laboratory of Molecular Biology

Observing the techniques at the Laboratory of Molecular Biology at Prof. Kusal Das’s Department.

Inter-institutional cooperation.

Inter-institutional cooperation.

Prof. Thuppil Venkatesh and myself also gave  talks at the engineering Department at BLDE, thanks to an invitation by Prof. Swastika Das.

Sharing the conference auditorium honor table with the Heads of the Engineering Departments at BLDE

Sharing the conference auditorium honor table with the Heads of the Engineering Departments at BLDE

Poster of our talks at the Engineering Department at BLDE

Poster of our talks at the Engineering Department at BLDE.

These were two very stimulating talks that generated much enthusiasm in the Professors and students of such a distinguished engineering School.

Receiving the flowers from Prof. Swastika Das, prior to the talk.

Receiving beautiful flowers from Prof. Swastika Das, prior to the talk.

Interesting moments with Prof. Kusal Das

Interesting moments with Prof. Kusal Das and Prof. Thuppil Venkatesh

I was also invited to be the External Examiner for a PhD Thesis by Dr S S Devarmani, Controller of Examination, BLDE University in reference to:

Thesis for PhD from BLDE University

Thesis for PhD from BLDE University

After an interesting presentation and round of questions by the assisting Professors of BLDE, and then followed by a closed meeting with further questions and recommendations, between the Three examiners: Prof. Kusal Das, Prof. Gustavo Zubieta-Calleja and Prof. Manjunath Aithal the guiding professor, along with the student Praveen S. Patil, we decided to accept  and approve the Thesis and I was granted the honor of announcing it to the candidate.

There were several other activities but upon returning to Bangalore, I was invited by Satish Jain, President of the Maharaja Agrasen Hospital,  to inaugurate the new Fertility Unit. Please see the video.

Aside from our Scientific cooperation with BLDE University with Prof. Kusal Das,  we are now proud to announce that Dr. Abbas Ali Mahdi has honored  me as:

Visiting Professor at Era University Lucknow, India

Visiting Professor at American University in Barbados

Thereby we establish a promising future collaboration association.

Our most profound thankfulness to Prof. Venkatesh and all his colleagues for the wonderful visit.

Poul-Erik (2)

Poul-Erik Paulev

Poul ErickPoul-Erik Paulev

One of the greatest Danish Physiologists

May 30, 1935 – June 25, 2017

In memoriam

I arrived with our two daughters, Natalia and Rafaela to Copenhaguen, Denmark on a chilly July back in 2004, in order to join my wife, Lucrecia De Urioste, who was acting as the 1st Secretary in Charge of Consular Affairs at the Bolivian Embassy. Six months previously, when her destiny to go there, had been set, I contacted through the web, Prof. Pouk-Erik Paulev at the Physiology Dept of the Panum Institute of the University of Copenhaguen. He responded “you are welcome in my lab”. From the Embassy, the following day after my arrival, I called Poul-Erik and we spent over an hour talking about our common interests in science. I immediately realized that I had, on the other side of the line, an extraordinary scientist!!

We talked about Ole Siggaard-Andersen, another Dane, the world’s father of acid-base status in blood, whom I admired greatly and with whom Poul-Erik was working. I was truly delighted and amazed! Many years back I had corresponded with Ole, regarding my interest of Acid-base and had even sent him the first computer interpretation of arterial blood gases and acid-base status, that I had written. So I could hardly believe my luck. At the end of our long telephone conversation, Pool-Erik told me to meet him at his office in the Panum Institute, next day.

When I knocked on his door, I found a tall, kind and a very enthusiastic man, with a pleasant smile who welcomed me effusibely. I immediately felt at home. He opened the door next to his Office and said, “this is your Office”. I could hardly believe it

Three and a half years of very productive pleasant scientific collaboration, ensued. We published joint papers related to high altitude, my specialty, in a country where the highest Point is a 170 m. hill.

I learned so much from him, in regards to scientific rigor, synthesis, pragmatism, simple minded attitudes, all, fundamental traits of superior men.

paulev-zubieta1

Shown here, a beautiful image of our collaboration at Panum Institute of Physiology, University of Copenhagen

He had been working on a review paper on the extraordinary achievements of the Danish scientists on acid-base equilibrium. I exposed to him the need to make high altitude corrections for the adequate interpretation in all high altitude cities of the world, a knowledge that would save lives. He became immediately interested and when I finished the calculations and the graphs, he decided to include a section in his review article and changed the title to “Essentials in the diagnosis of Acid-Base Disorders and it’s High Altitude Application“. He offered to put my name as first author and I refused. Then, I came up with the idea of tossing a coin, that upon flipping in the air and dropping to the ground, favored him. We laughed and carried on and write in all, 8 papers together. The subjects were diverse including high altitude diving tables. He came to our III Chronic Hypoxia Symposium with his lovely wife Kirsten. Some photos can be seen here.

His generosity went beyond limits. He wrote a physiology book and put it on-line for free use, by anyone. Later on, he granted me co-authorship and I wrote the High Altitude section. Kirsten McCord, one of his patients had discovered his personality and collaborated with him making the graphs, that are now so famous in many physiology books. She went on to become a lifetime collaborator and friend always visiting Poul-Erik and his lovely wife Kirsten that always greeted us with a smile and great Smorebrød (typical Danish sandwiches) at their enchanting home in Birkerød, right next to the golf course, where Poul-Erik and his wife Kirsten, spent many hours enjoying the fields.

I throughly enjoyed discussion of many aspects of physiology and science in his lab. He told me very interesting stories, like when he was a young man and wrote an article that questioned the concepts of Herman Rahn, who was a notable German physiologist who had moved to US. He pointed out that Herman had not been upset, quite the contrary, he invited Poul-Erik to spend some time in his lab. He also told me that Herman had a small scale in his pocket and ran out everyday from his office to the garden to weigh an egg of a small byrd in his nest, that way he was able to study hydration of the egg. That was a time of superior scientists, that made fantastic advances in science. There was no mediocrity, that my father once referred to as: “a congenital disease, very painful and with no treatment”.

Poul-Erik wrote a beautiful and concise biography. I insisted that it be longer, but he was always precise and to the point. It can be read here. Noteworthy is the fact that he suspected decompression sickness when most thought that there was a toxic effect in the water. It is important to note that while at the Panum Institute, I noticed that many of his colleagues were jealous of his work. They had tried to outs him from his teaching on several occasions, but could  not do so because he had so many scientific publications, more than any of his colleagues. When I joined him and we worked together, I noticed a lot of jealousy about his work and I of course had to inherit this unnoble attitude towards him. But to simply spend life together with him, and to share the most beautiful moments together, in science and deep nearly parental friendship, was more than welcome.

Poul-Erik had worked as a young scientist, in the study of rescuing sailors from submarines. He performed many dives in a 20 meter pool specially designed in order to develop rescue techniques. He dived so many times that on one occasion upon coming up too fast he developed the “bends” (decompression sickness), that he referred to as very painful. He was immediately put of a hyperbaric chamber where he had to spend many hours and upon exit, he again presented pains so he returned for some more hours. This stimulated his interest in diving physiology. he wrote several papers, and I joined him in a few. We wrote about high altitude diving in Lake Titicaca and higher lagoons. This lead to the creation of the Poul-Erik Paulev High Altitude Laboratory

There he wrote a most beautiful, concise and admirable autobiography. We travelled jointly to a meeting in Poland to join his friend Pokorsky of the Polish Science Academy. We also went to a meeting in Berlin. He asked me to replace Bengt Saltin in a course on acid-base in the north of Denmark, where we attended jointly with our wives. Thanks to their generosity we were able to integrate our family in the fascinating life of Danish culture, of which we became great admirers. I even wrote an article on Danish education in the Copenhagen Post.

He came with Kirsten, to the III Chronic Hypoxia Symposium that I organized in Bolivia. I created the Poul-Erik High Altitude Diving Laboratory in our building.

There we also met Pernille, Thomas and Matias, wonderful, wonderful Danés, He had 3 daughters and Kirsten has 2 sons.

I have difficulty expressing, when I write these words, about this extraordinary man, of all his scientific and human greatness!!

Had the world been populated by more people like him, we would all live in Paradise.

I express my profound admiration for his extensive and wisdom filled scientific work, of over 160 articles published in prestigious Journals around the world. Many are available at Researchgate.net. What a great Danish Physiologist he was. He left us on July 2017, when he decided it was time time to leave at 84 years of age after a  heroic battle with Parkinson’s Disease.

His legacy is scientific, and I bow to always remind all scientists around the world, about his outstanding achievements.

Prof. Dr. Gustavo Zubieta-Calleja

Hyaena Potosi Mountain near La Paz, (photo courtesy of Giuseppe MIsserochi)

6th Chronic Hypoxia Symposium Follow-up

Chronic Hypoxia Symposium VI – Follow-up

Oct 10 – 16, 2016
La Paz, Bolivia

Dedicated to the late Prof. Dr. Gustavo Zubieta-Castillo

Prof. Dr. Gustavo Zubieta-Castillo "The Mountain Guru"

Prof. Dr. Gustavo Zubieta-Castillo “The Mountain Guru”

This unique itinerant symposium was a gathering of participants from around the world, all sharing a common interest in the wonder of the mountain environments, whether through research or other endeavors. With Chairman Dr. Gustavo Zubieta-Calleja at the helm, assisted by his family, medical students and Dr. Fabian Wayar. This symposium convened in La Paz (3100 – 4100m), and was generously supported by the High Altitude Pulmonary and Pathology Institute (IPPA) with collaboration by the Bolivian Navy, the La Paz Medical College and its President, Dr. Luis Larrea and the Universidad Franz Tamayo “Unifranz.” All were engaged in the lively presentations, and were wholly encouraged to participate in topic discussions.

Details of the Conference

The conference presentations were given almost exclusively in English. Attendees met in the Unifranz on the first day on Monday Oct 10, 2016, where opening words were given by Prof. Dr. Gustavo Zubieta-Calleja, Director of the High Altitude Pulmonary and Pathology Institute (IPPA) and Dr. Thuppil Venkatesh, President of the International Society of Chronic Hypoxia. This symposium was poignantly dedicated in the memory of the incomparable Dr. Gustavo Zubieta-Castillo, whose life was devoted to the study of hypoxia and the care of patients suffering from altitude illness. A presentation by Dr. Zubieta-Castillo’s granddaughter, Natalia Zubieta, highlighted his life’s work. Conference participants were provided with books commemorating Dr. Zubieta-Castillo with quotes from colleagues who respected and admired him and his work from around the globe.

First day of conferences

First day of conferences

Dr. Giuseppe Miserocchi, former Professor of Physiology and Biophysics at the University Milano-Bicocca in Italy, gave an enlightening talk on the Inter-individual Differences in the Adaptive Response of the Lung to Hypoxia. Dr. Miserocchi described the conditions leading to lung edema, including miscrovascular permeability and increased cardiac output, versus the conditions opposing it, including interstitial matrix rigidity, vasoconstriction in pulmonary microcirculation, and reduced capillary patency. Variations exist among human response to diffusion capacity of the lungs during hypoxia, with more than half of the subjects showing an increase in alveolar membrane diffusing capacity that overpowered the decrease in lung capillary blood volume.

Dr. Zubieta-Calleja gave a lively presentation regarding The Road to “Defeating Hypoxia” is a timely exposure to chronic hypoxia. He also discussed polyerythrocythemia as a precise terminology developed by the late Prof. Dr. Gustavo Zubieta-Castillo, to be used instead of chronic mountain sickness. He reiterated the simple yet powerful formula:

Adaptation =  time / altitude

Dr. Zubieta-Calleja challenged the belief that people life’s under chronic hypoxia is debilitating, arguing that many conditions may be treated with exposure to hypoxia. He gave evidence of increased longevity among high-altitude dwellers. He punctuated his talk by climbing on a chair and “punching” hypoxia, breaking it into pieces that fell down in the screen, to emphasize its defeat!

A tour through the city of La Paz

A tour through the city of La Paz. Walter Calderon (Peru), Willy Cortez (Bolivia), K.V.R. Tagore (India), Naanjapa  Rajashepar (India), Satish Jain (India) , Sadashivaiha (India), Annie Wislowski (USA), Jose Antonio Carmona (Mexico), Benedito Machado (Brazil).

After several breaks, in which the conference attendees enjoyed tasty local cuisine such as salteñas, cunapes, and galletas, Dr. Benedito Honorio Machado from the School of Medicine of Riberao Preto in the University of Sao Paolo, Brazil presented “Neural Mechanisms Involved in Autonomic and Respiratory Changes in Rats Submitted to Short-Term Sustained Hypoxia.” In this talk, Dr. Machado described the role of short-term sustained hypoxia on anesthetized rats in increasing the sympatho-inhibitory and bradycardiac components of baroreflex, as well as the sympathetic and respiratory responses of peripheral chemoreflex. They found hypoxic exposure was associated with increased excitation of the nucleus tractus solitarius neurons on the carotid body and aortic depressor nerve. Changes in glial density were also noted.

Dr. Alla Portnychenko, Head of the International Centre for Astronomical, Medical and Ecological Research, NAS of Ukraine presented via webcam “Rebuilding of carbohydrate and lipid metabolism under hypoxia: Regularities and therapeutic possibilities.” Her studies on rats showed activation of hypoxia inducible factor 1a (HIF-1a) and -3 a subunits during hypoxia, resulting in the induction of GLUT-4 and -1 in the myocardium and lungs. This resulted in a change from carbohydrate to predominantly lipid substrate up-regulation. In humans, they found changes in cholesterol metabolism, leptin and insulin-growth factor IGF-1 plasma levels, and positive correlation with HIF-dependent protein IFG-1 and HDL-cholesterol. She concluded with the intriguing suggestion that hypoxia might be used to correct metabolic disorders in some people.

Dr. Zoya Serebroska of the Bogomoletz Institute of Physiology in Ukraine presented via webcam “Potential application of cerium dioxide nanoparticles for acute pneumonia treatment.” She and her team found that CeO2 nanoparticles significantly reduced morphological and functional pulmonary damage in rats after exposure to pneumonia. It was noted that Dr. Serebroska’s mother Dr. Tatiana Serebrovskaya, also a hypoxia researcher, was one of the first to suggest the role of nitric oxide as an important molecule in vasodilatory regulation.

Dr. Walter Calderon of the Hospital Nacional Ramiro Prialé, EsSalud, Huancayo, Junín, Perú and the Universidad Nacional del Centro del Perú, Huancayo, Perú presented “Prospective Validation of Framingham Criteria for Congestive Heart Failure diagnosis in a High Altitude Population” He noted that sensitivity was 98.6% for patients with Heart Failure, but specificity of these criteria were only 12% among patients who presented with dyspnea and at least one of the major Framingham criteria. He showed a compelling picture of collateral circulation from a cardiac cath.

Dr. Jose Antonio Carmona Suazo of the Hospital Juarez in Mexico presented “CO2 reactivity, a tool for prevention of HACE (High Altitude Cerebral Edema): Hands-on workshop.” He gave an exciting hands-on demonstration of the non-invasive and safe ability to monitor the level of  cerebral blood flow, ETCO2 in humans at altitude. Cerebral and respiratory effects were measured on Dr. Thuppil Venkatesh, who happily volunteered.

The Tiwanaku Código 0.4666 was presented by Willy Eduardo Cortez Hemzler, Investigador y Artista Plástico. Señor Cortez described how he discovered that the ratio of the length and width of the building materials at Tiwanaku equals 0.46, which is maintained throughout the structures. He showed the relationship of 0.46 to the radius of a circle.

After this, participants were treated to a bus tour of the city of La Paz.and the Inauguration Ceremony was held at the IPPA Building auditorium.

Inauguration ceremony, at the IPPA building auditorium. From Left (Prof. Thuppil Vnekatesh, The La Paz, Mayor's representative, Prof. Dr. Gustavo Zubieta-Calleja, Dra. Representative of the Colegio Medico, and Celeste representing Unifranz.

Inauguration ceremony, at the IPPA building auditorium. From Left (Prof. Thuppil Vnekatesh, The La Paz, Mayor’s representative, Prof. Dr. Gustavo Zubieta-Calleja, Dra. Representative of the Colegio Medico, and Celeste representing Unifranz.

It was a lively ceremony, with honored by the presence of 4 ambassadors (Great Britain, Mexico, European Union and Italy) and the representative of the Consulate of India, along with the representatives of the La Paz Medical College, Unifranz and the Bolivia. The La Paz Mayor’s office through its representative, granted Prof. Thuppil Venkatesh the “Huesped Ilustre de la ciudad de La Paz” (Distinguished Guest of the city of La Paz), normally given only to outstanding personalities (like Presidents) that visit our city.

Inauguration ceremony with the presence of 4 Ambassadors (England: James Thornton, Mexico: Hector Valezzi, European Union: Leon De la Barca and Italy: Placid Vigo, and also the representative of the Consul of India (Jorge Velasquez).

Inauguration ceremony with the presence of 4 Ambassadors (England: James Thornton, Mexico: Hector Valezzi, European Union: Leon De la Barca and Italy: Placid Vigo, and also the representative of the Consul of India (Jorge Velasquez).

Prof. Thuppil Vnelatesh with his Illustrious visitor award granted by the La Paz, Mayor's Office.

Prof. Thuppil Vnelatesh with his Illustrious visitor award granted by the La Paz, Mayor’s Office.

On Tuesday, October 11, participants left early in the morning to the ruins Tiwanaku and the Archaeological Museum, at 3800m. The morning provided a fascinating tour of the grounds of unknown age. Willy Eduardo Cortez Hemzler was the impromptu tour guide. The attendees also saw the big Monolito Bennet  at Tiwanaku, and visited the ruins of Punta Punku, believed to be even older than Tiawanaku.

Annie Wislowski, the writer of this follow-up, during the visit to Tiawanacu. (photo courtesy of Annie Wislowski)

Annie Wislowski, the writer of this follow-up, at the  Sun Door, during the visit to Tiawanacu. (photo courtesy of Annie Wislowski)

After this intriguing look at Bolivian history and life since ancient times at high altitude, participants had a late lunch on the Barco Multiproposito of the Bolivian Army. We were received in true elegance and style by the Army. Talks continued with Dr. Giuseppe Miserocchi continuing his presentation on “Inter-individual differences concerning the oxygen diffusion-transport function in the lung.” One fascinating thing we learned was that middle-distance runners tend to fare poorly at altitude, due to  increased permeability at the alveolar level!

Next, presented Rajashekar Nanjappa of the Regional General Manager, THE HINDI NEWSPAPER, Bengaluru, India Media & Mountain Medicine A Commitment: Role and Impact of Media on Society and with Special reference to Newspapers role in Public Awareness. He focused on the endeavors of LESAAT which has organized treks at high-altitude around the globe.

After these presentations, attendees returned to La Paz at Unifranz and viewed the poster competition entries. These were “Development and validation of new sepsis criteria at high altitude” by Dr. Walter Calderon-Gerstein, and “Spirometry values of high-rise residents” of La Paz, Bolivia by one of the medical students, both awarded the 100 US$ price donated by Prof. Thuppil Venkatesh, President of the International Society of Chronic Hypoxia.

Performing tests at the Titicaca Lake with Dr. Jose Antonio Carmona and Yeshua Peña Y Lillo (medical student working with Prof. Dr. Gustavo Zubieta-Calleja. (photo courtesy of Lucrecia De Urioste)

Performing tests at the Titicaca Lake with Dr. Jose Antonio Carmona and Yeshua Peña Y Lillo (medical student working with Prof. Dr. Gustavo Zubieta-Calleja. photo courtesy of Lucrecia De Urioste)

Measuring ETCO2, NIRS, brain waves and more with sophisticated technology brought by Dr. Jose Antonio Carmona for the Work Shop.

Measuring ETCO2, NIRS, brain waves and more with sophisticated technology brought by Dr. Jose Antonio Carmona for the Work Shop.

On Wednesday, October 12, participants rose early for the bus ride to Lake Titicaca at 3800m. Participants visited the High Altitude Diving Training Center in Tiquina.

Arrival to the Titicaca Lake

Arrival to the Titicaca Lake

Here, talks were given by the Comander of the Diving Center, Cap. Chavez who described in Spanish the history and workings of the Dive Center (CIBA) and the challenges encountered while diving at altitude (buceo en altura). After a delicious lunch tasting the high altitude lake trout, participants toured the hyperbaric chamber and the hospital boat located on the base.

The Commander of the High Altitude Diving Center of the Bolivian Navy givin a talk about their experience.

The Commander of the High Altitude Diving Center of the Bolivian Navy givin a talk about their experience.

Other talks that day included “Low Altitude Peripheral Edema (LAPE): The opposite of HAPE or HACE” by Prof. Dr. Gustavo Zubieta-Calleja, on the swelling (positive Godet sign) that occurs when high-altitude residents spend time in low-altitude environments. He described the changes in sialic acid levels obtained from red blood cells in his family after a trip to low-altitude destinations in India.

During the beautiful boat ride by the Bolivian Navy.

During the beautiful boat ride by the Bolivian Navy.

A pre-recorded lecture by Dr. Sadykova from the Institute of Mountain Physiology National Academy of Sciences, Kyrgyz Republic described the neuroendocrine changes occurring at altitude. Among those, elevated norepinephrine, dopamine, serotonin, TSH and T4, and a reduction of testosterone and T3 were noted.

Visiting the Hyperbaric Chamber at the CIBA, Bolivian Navy facilities.

Visiting the Hyperbaric Chamber at the CIBA, Bolivian Navy facilities.

KVR Tagore, President of LESAAT, then described “Mountains – Law – Ethics ,” and discussed the importance of protecting mountains as precious resources through sustainable tourism.

Finally, Willy Eduardo Cortez Hemzler took time to finish his lecture from Monday on Tiwanku and the code of 0.466.

After these presentations, attendees returned to La Paz at Unifranz and viewed the poster competition entries. Two  were granted the first prize of 100 US$ donated by Prof. Thuppil Venkatesh, President of the International Society of Chronic Hypoxia. These were: “Development and validation of new sepsis criteria at high altitude” by Dr. Walter Calderon-Gerstein, and “Spirometry values of high-rise residents” of La Paz, Bolivia by one of the medical students.

Hyaena Potosi Mountain near La Paz, (photo courtesy of Giuseppe MIsserochi)

Hyaena Potosi Mountain near La Paz, (photo courtesy of Giuseppe MIsserochi)

On Thursday, October 11, participants traveled initially to the Refugio of Huayna Potosi and later to Chacaltaya (5260m). Scores of llamas and alpacas were photographed by the curious attendees, some of whom even got to view a glimpse of the shy and reclusive vicuña!

Llama staring at the high altitude experts on their way to Chacaltaya. (photo courtesy of Giuseppe Misserochi)

Llama staring at the high altitude experts on their way to Chacaltaya. (photo courtesy of Giuseppe Misserochi)

In Chacaltaya, Nam Deo of Bangalore, India gave a talk “Vihangam Yog helps in high altitude chronic hypoxia” and led the group in meditation on the shoulder of the mountain.

The visit to Huayna Potosi and Chacaltaya

The visit to Huayna Potosi and Chacaltaya at 5300m

Interestingly, one of the participants reported that her pulse oximetry reading increased from 89% to 93% after the meditation session, Dr. Zubieta-Calleja, explained that as reported in one of his papers, breath holding at high altitude can momentarily increase the SpO2 to even sea level values of 98%.. Dr. Thuppil Venkatesh then gave a speech about “Life in high altitude conditions.” Prof. Sadashivaya, gave an interesting talk about the importance of “forestation at high altitude”. Prof. Nanjapa of the Hindu Newspaper talked about high altitude and the media, K.V.R Tagore talked about philosophical aspects of mountain climbing. Prof. Satish Jain also mentioned about his experience with high altitude.

Finally Prof. Dr. Gustavo Zubieta-Calleja, gave a talk about the evolution of high altitude medicine, the tolerance to hypoxia at high altitude and thanked everyone for participating in this outstanding symposium, where the visit to different altitude sights to show normally developing life is a one of the fundamental objectives of defeating the wrong concepts of hypoxia.

All these talks filmed outdoors with the Chacaltaya Pyramid “the highest laboratory in the world 5250m)” (shown in the background), created by the late Prof. Dr. Gustavo Zubieta-Castillo and his son Prof. Dr. Gustavo Zubieta-Calleja, in conjunction with the Club Andino Boliviano.

dsc_1308

Upon returning to La Paz, a dinner and closing ceremony was held at the residence of Prof. Dr. Gustavo Zubieta-Calleja in the southern residential area of Calacoto. It was a special gathering where Dr. Satish Jain assisted in preparing some food from India, along the food that Lucrecia De Urioste with her assistant, Lucia, Natalia and Rafaela so beautifully presented for all those attending. Some talks also took place here.

Closing dinner conferences

Closing dinner conferences

The Science, Honor and Truth Award, went this year to Prof. Kusal Das, being sent by Prof Thuppil Venkatesh.

The Science, Honor and Truth Award, went this year to Prof. Kusal Das, being given personally by Prof Thuppil Venkatesh on his return to India.

 

Conferences at the Closing Dinner.

Conferences at the Closing Dinner.

Dr. Giuseppe Misserochi presented Dr. Zubieta-Calleja with a gift of a water color painting of the Cordillera, that he personally painted while enjoying the beatufil mountains around La Paz.

Watercolor painting of the andes Cordillera by Prof. Misserochi.

Watercolor painting of the Andes Cordillera by Prof. Misserochi.

Nam Deo from India, leaded everyone in a meditation session in the living room.

Nam Deo's meditation session in the closing dinner.

Nam Deo’s meditation session in the closing dinner.

Awards and certificates were presented and the Symposium was closed.

Closing ceremony and birthday cake celebration. Dr. Satish Jain, Prof. Dr. Gustavo Zubieta-Calleja, Rafaela, Lucrecia De Urioste, Natalia, Dr. Walter Calderon

Closing ceremony and birthday cake celebration. Dr. Satish Jain, Prof. Dr. Gustavo Zubieta-Calleja, Rafaela, Lucrecia De Urioste, Natalia, Dr. Walter Calderon

The colleagues and friends from India, joined us in a trip to visit the incredible Salt Lake, Potosi and Sucre. Life at high altitude flourishes everywhere!

Prof. Giuseppe Misserochi pondering about the Salt Lake.

Prof. Giuseppe Misserochi pondering about the Salt Lake.

See you in the VII Chronic Hypoxia Symposium in two years!!

 

written by Annie Wislowski

Edited by Prof. Dr. Gustavo Zubieta-Calleja

India Chronic Hypoxia Tour – Kolar

Grand Chronic Hypoxia Tour throughout India July 2016 in the city of Kolar

In this series of consecutive blogs, you can read about this outstanding scientific tour. Each blog is dedicated to one city and one scientific concept presented in the conference “Extraordinary Adaptation to Chronic Hypoxia and Life at High Altitude”

Back to Day 1 of the India Chronic Hypoxia tour

The trip to Kolar was very pleasant as Prof. Thuppil Venkatesh and myself were picked up from Bangalore in a very nice car from the SDUAHER University.

Dr. K.N. Shashidhar Welcomes Prof. Dr. Gustavo Zubieta-Calleja and Dr. Thuppil Venkatesh

Dr. K.N. Shashidhar Welcomes Prof. Dr. Gustavo Zubieta-Calleja and Dr. Thuppil Venkatesh.

Dr. K.N. Shashidhar Professor and HOD Biochemistry, Sri Devaraj Urs Academy Of Higher Education and Research.

 

Sitting : Left to right; Prof. (Dr) Raghuveer, Hon. Vice Chancellor,Sri Devaraj Urs Academy Of Higher Education and Research, Dr Tuppil Venkatesh, Yourself, Prof. (Dr) AVM Kutty, Registrar,Sri Devaraj Urs Academy Of Higher Education and Research, Myself; Dr Shashidhar Professor and HOD Biochemistry, Sri Devaraj Urs Academy Of Higher Education and Research

Sitting : Left to right; Prof. (Dr) Raghuveer, Hon. Vice Chancellor,Sri Devaraj Urs Academy Of Higher Education and Research, Dr Tuppil Venkatesh, Yourself, Prof. (Dr) AVM Kutty, Registrar,Sri Devaraj Urs Academy Of Higher Education and Research, Myself; Dr Shashidhar Professor and HOD Biochemistry, Sri Devaraj Urs Academy Of Higher Education and Research

 

Left to Right: Prof. K.N.Shashidhar , Prof. (Dr) Raghuveer and Prof. Dr. Gustavo Zubieta-Calleja heading to the conference room.

Left to Right: Prof. K.N.Shashidhar , Prof. (Dr) Raghuveer and Prof. Dr. Gustavo Zubieta-Calleja heading to the conference auditorium.

The sign announcing the conference.

The sign announcing the conference.

Prof. K.N. Shashidhar introducing Prof. Dr. Gustavo Zubieta-Calleja's conference

Prof. K.N. Shashidhar introducing Prof. Dr. Gustavo Zubieta-Calleja’s conference

Prof. Dr. Gustavo Zubieta-Calleja giving his conference on Chronic Hypoxia.

Prof. Dr. Gustavo Zubieta-Calleja giving his conference on Chronic Hypoxia.

Dr. Anantha Bhattacharya, Assistant Prof. preventive and Social Medicine, Sri Devaraj Urs Academy Of Higher Education and Research.

Dr. Anantha Bhattacharya, Assistant Prof. preventive and Social Medicine, Sri Devaraj Urs Academy Of Higher Education and Research handing a post conference beautiful gift..

A group photo after the conference with some of the faculty of  Sri Devaraj Urs Academy Of Higher Education and Research.

A group photo after the conference with some of the faculty of Sri Devaraj Urs Academy Of Higher Education and Research.

Prof. Dr. Gustavo Zubieta-Calleja, Prof. (Dr) Raghuveer, Hon. Vice Chancellor, Prof. (Dr) AVM Kutty, Registrar, Prof. Thuppil Venkatesh and Prof. K.N. Shashidhar

Prof. Dr. Gustavo Zubieta-Calleja, Prof. (Dr) Raghuveer, Hon. Vice Chancellor, Prof. (Dr) AVM Kutty, Registrar, Prof. Thuppil Venkatesh and Prof. K.N. Shashidhar

I left with a very good impression of the quality of SDUAHER University in Kolar.

Click here to go to the next day of the GRAND CHRONIC HYPOXIA TOUR IN INDIA – BELLARY.

Back to Day 1 of the India Chronic Hypoxia tour

 

 

 

 

Grand Chronic Hypoxia Tour – Kochi

Grand Chronic Hypoxia Tour throughout India July 2016 in the city of Kochi

In this series of consecutive blogs, you can read about this outstanding scientific tour. Each blog is dedicated to one city and one scientific concept presented in the conference “Extraordinary Adaptation to Chronic Hypoxia and Life at High Altitude”.

Back to Day 1 of the India Chronic Hypoxia tour

After visiting Mumbai with its beautiful airport, where we spent the night at a beautiful apartment and a brief tour of the Gateway to India, we flew to Kochi.

The Mumbai Gateway to India

The Mumbai Gateway to India

 

Hosted by Varkey, President of the Lions Club in Kochi, along with his wife, we were given the wonderful surprise that at 10:00 am we could go to the Mariott for a couple of hours to freshen up. It was so beautiful, and so comfortable. Our IPPA team, Prof. Dr. Gustavo Zubieta-Calleja, Lucrecia De Urioste Limariño, Natalia Zubieta De Urioste and Rafaela Zubieta de Urioste, along with our luxury travel team Prof. Thuppil Venkatesh and Prof. Shashisdhara, then moved to the Amrita Hospital, where Gustavo Zubieta-Castillo (Sr) and Gustavo Zubieta-Calleja (Jr) had participated several years back in a conference on Clinical Biochemistry.

 

Giving the Conference at Amrita Hospital installations

Giving the Conference at Amrita Hospital installations

This time again we were warmly greeted at Amrita by Dr. Sanjeev K. Singh, Medical Superintendent.

Natalia giving her interesting comments on chronic hypoxia aspects . Dr. Sanjeev K. Singh is to the far right

Natalia giving her interesting comments on chronic hypoxia aspects . Dr. Sanjeev K. Singh 4th from left.

ONE CONCEPT INCLUDED IN THE CONFERENCE “Extraordinary Adaptation to Chronic Hypoxia and Life at High altitude”:

The extraordinary population of a city life La Paz, and El Alto that is like any other matronly in the world. Everyone lives busy and totally unaware of their life at high altitude. They are born here, grow, study, do sports, get married, have children and all in the chronic hypoxia environment uneventfully.

Dr. Thuppil Venkatesh commenting about how high altitude dwellers can suffer from the effects of hyperoxia.

Dr. Thuppil Venkatesh commenting about how high altitude dwellers can suffer from the effects of hyperoxia.

Prof. Dr. Gustavo Zubieta-Calleja’s conference on “Extraordinary Adaptation to Chronic Hypoxia”.

 

We again visited the unique antique shops in Kochi with the kind hosting of Varkey and his lovely wife Sarada Varkey.

Prof. N. Shashidhara, Lucretia De Urioste and Mrs. Sarada Varkey

Prof. N. Shashidhara, Lucretia De Urioste and Mrs. Sarada Varkey

Prof. N. Shashidhara, Prof. Thuppil Venkatesh and Prof. Dr. Gustavo Zubieta-Calleja at Kochi.

Prof. N. Shashidhara, Prof. Thuppil Venkatesh and Prof. Dr. Gustavo Zubieta-Calleja at Kochi.

T.A. Varky, the President of the Lions Club in Kochi and also the director of several Clinical Laboratories. Alongside is Sarada Varkey, his wife.

T.A. Varky, the President of the Lions Club in Kochi and also the director of several Clinical Laboratories. Alongside is Sarada Varkey, his wife.

 

Click here to go to the next day of the GRAND CHRONIC HYPOXIA TOUR IN INDIA – KOLAR

Back to Day 1 of the India Chronic Hypoxia tour

India Grand Chronic Hypoxia Tour – Bangalore Final

Grand Chronic Hypoxia Tour throughout India July 2016 in the city of Bangalore last stop

In this series of consecutive blogs, you can read about this outstanding scientific tour. Each blog is dedicated to one city and one scientific concept presented in the conference “Extraordinary Adaptation to Chronic Hypoxia and Life at High Altitude”.

Back to Day 1 of the India Chronic Hypoxia tour

 

St. Philomena's Church

St. Philomena’s Church at Mysore.

 

Conference at the Exclusive Century Club in Dehli kindly hosted by K.V.R. Tagore and Prof. Thuppil Venkatesh.

Mr. K>V> Tagore introducing the speaker Prof. Dr. Gustavo Zubieta-Calleja at the Century Club in Bangalore, India

Mr. K>V> Tagore introducing the speaker Prof. Dr. Gustavo Zubieta-Calleja at the Century Club in Bangalore, India

 

Prof. Dr. Gustavo Zubieta-Calleja giving his talk. at the Century Club

Prof. Dr. Gustavo Zubieta-Calleja giving his talk. at the Century Club

Touching the aspect of Adaptation to life at the hypoxic levels of Mt. Everest.

Touching the aspect of Adaptation to life at the hypoxic levels of Mt. Everest.

 

Group photo at the Century Club conference.

Group photo at the Century Club conference.

 

A visit to the house of K. Raghunath, where we met his beautiful family and he honored us by playing 4 pieces in violin with his son accompanying him with a harmonica. The Indian music was such a great delight that it still resonates in our minds.

At K. Raghunath's house where we heard the most beautiful Indian music.

At K. Raghunath’s house where we heard the most beautiful Indian music.

 

A camel ride !!!

A camel ride !!!

The end of this fantastic scientific and cultural voyage throughout Incredible India. Thank you very much, from the deepest of our hearts, as Bolivians for all your kindness and generosity, that are a true example to the world!!

Back to Day 1 of the India Chronic Hypoxia tour

 

 

Rafaela being blessed by the elephant in one of the temples near Hampi

Grand Chronic Hypoxia Tour India – Bellary

Grand Chronic Hypoxia Tour throughout India July 2016 in the city of Bellary

In this series of consecutive blogs, you can read about this outstanding scientific tour. Each blog is dedicated to one city and one scientific concept presented in the conference “Extraordinary Adaptation to Chronic Hypoxia and Life at High Altitude”.

Back to Day 1 of the India Chronic Hypoxia tour

Bellary, Bellary, Bellary……..  is what we heard on arrival by train to this lovely city. We thought we had slept past the station, so it was a great relief! In this area, memorable and extraordinary  temples are found. Among them, the unforgettable Hampi !!.

The Mumbai Gateway to India

The Mumbai Gateway to India

One of the many Hampi buildings. This one has columns that were used as musical instruments.

One of the many Hampi buildings. This one has columns that were used as musical instruments.

 

Inside one of the buildings at Hampi.

Inside one of the buildings at Hampi.

Rafaela being blessed by the elephant in one of the temples near Hampi

Rafaela being blessed by the elephant in one of the temples near Hemp

 

With the great Stone Chariot at Hampi . Prof. Thuppil Venkatesh, Prof. Shashidhara, Prof. Dr. Gustavo Zubieta-Calleja, Rafaela Zubieta, and our fantastic host and organizer of our visit to Belari and the conferences with Red Cross M.A. Shake.

With the great Stone Chariot at Hampi . Prof. Thuppil Venkatesh, Prof. Shashidhara, Prof. Dr. Gustavo Zubieta-Calleja, Rafaela Zubieta, and our fantastic host and organizer of our visit to Belari and the conferences with Red Cross M.A. Shakeeb.

 

Breakfast meeting with the Red Cross officials kindly organized by K.V. Shakeeb. at Bellary.

Breakfast meeting with the Indian Red Cross officials kindly organized by Commander K.V. Shake (in red). at Bellary.

Another angle of the same meeting with the red Cross.

Another angle of the same meeting with the Officials of the Indian  Red Cross.

Conference at VIMS Bellary (Vijayanagar Institute of Medical Sciences). on Remarkable Adaptation to Chronic Hypoxia).

Conference at Veerashaiuva College, Ballari. for the Indian Red Cross on Remarkable Adaptation to Chronic Hypoxia. Presence of the Vice-Chancellor.

ONE CONCEPT INCLUDED IN THE CONFERENCE “Extraordinary Adaptation to Chronic Hypoxia and Life at High altitude”:

The Triple Hypoxia Syndrome (THS) created by Prof. Dr. Gustavo Zubieta-Castillo, was explained. It is due to the superimposition of three different types of hypoxia: [1] Normal high altitude adaptation to hypoxia, [2] Polyerythrocythemia hypoxia (CMS) and [3] acute hypoxia that can be reversed by oxygen. The THS is similar to “surviving” in the summit of Mount Everest. It may be caused by viral infections (gripe) or some other acute respiratory disease, with malaise that lasts several days without treatment and typically is reversed by 24 hours of oxygen to PaO2 baseline values of their chronic condition with Polyerythrocythemia (The sign that results from multiple diseases at high altitude, previously known as Chronic Mountain Sickness). This diagnosis is fundamental to treat patients with increased Hematocrits at high altitude.

 

Conference at VIMS Bellary (Vijayanagar Institute of Medical Sciences) Group photo.

Conference at  Veerashaiva College, Ballari Group photo.

 

Plaque of all the authorities of the Veerashaiva College, Ballari

Plaque of all the authorities of the Veerashaiva College, Ballari

A visit to the President's office

A visit to the President’s office

Click here to go to the next day of the GRAND CHRONIC HYPOXIA TOUR IN INDIA – BIJAPUR AND A CONFERENCE AT THE BLDE UNIVERSITY.

Back to Day 1 of the India Chronic Hypoxia tour

A beautiful powder and flower design specially prepared for the conference on 
Environmental Physiology.

Grand Chronic Hypoxia Tour – Karad

Grand Chronic Hypoxia Tour throughout India July 2016 in the city of Karad

In this series of consecutive blogs, you can read about this outstanding scientific tour. Each blog is dedicated to one city and one scientific concept presented in the conference “Extraordinary Adaptation to Chronic Hypoxia and Life at High Altitude”.

Back to Day 1 of the India Chronic Hypoxia tour

Dr. Arun Patil, arranged our visit to the Krishna Institute of Medical Sciences Deemed University. The gardens of the campus were truly beautiful.

Reception at the Chancellor's office in the Krishna Institute of Medical Sciences Deemed University in Karad.

Reception at the Chancellor’s office in the Krishna Institute of Medical Sciences Deemed University in Karad.

A beautiful powder and flower design specially prepared for the conference on  Environmental Physiology.

A beautiful powder and flower design specially prepared for the conference on
Environmental Physiology.

Inauguration ceremony of the Environmental Physiology conference at the Krishna Institue of Medical Sciences in Karad

Inauguration ceremony of the Environmental Physiology conference at the Krishna Institue of Medical Sciences in Karan

Prof. Dr. Gustavo Zubieta preparing his conference on "Extraordinary Adaptation to Chronic Hypoxia" at the Krishna Institute of Medical Sciences.

Prof. Dr. Gustavo Zubieta preparing his conference on “Extraordinary Adaptation to Chronic Hypoxia” at the Krishna Institute of Medical Sciences.

ONE CONCEPT INCLUDED IN THE CONFERENCE “Extraordinary Adaptation to Chronic Hypoxia and Life at High altitude”:

The proposal of IPPA of the use in Space Vehicles of the environmental oxygen levels, PIO2 of 94 mmHg (1/3 less than at sea level) equal to those of the city of La Paz. This would facilitate travel in space tremendously, as it would speed up the preparation for using the space suits for extravehicular activities, it would save oxygen (a scare resource in space) and would hence save energy. Furthermore, it is postulated that man should adapt to chronic hypoxia for the future. The benefit of life under chronic hypoxia are remarkable.

Kind Felicitation of Prof. Dr. Gustavo Zubieta-Calleja

Kind Felicitation of Prof. Dr. Gustavo Zubieta-Calleja by Dr. Ajay Brahmnakar Hon. Asst Professor K.I.M.S.D.U, Karat.

Profesor Thuppil Venkatesh giving his talk on the effects  of Lead on the organism.

Profesor Thuppil Venkatesh giving his talk on the effects of Lead on the organism.

Prof. Kusal Das from BLDE University came to Karad to participate in the Environmental Physiology event and presented a very interesting talk on Fluoride intoxication in water resources.

Prof. Kusal Das from BLDE University came to Karad to participate in the Environmental Physiology event and presented a very interesting talk on Fluoride intoxication in water resources.

In the photo above: From left Prof. Dr. Gustavo Zubieta-Calleja, Prof. Kusal Das, Sayandeep (Prof. Kusal Das’ son and a 1st year medical student), Mrs. Swastika (Professor Kusal Das’ wife) and Rafaela Zubieta.

Dr. Arun Patil our excellent coordinator and the Zubietas in Karad, India, after the conference.

Dr. Arun Patil our excellent coordinator and the Zubietas in Karad, India, after the conference.

 

Click here to go to the next day of the GRAND CHRONIC HYPOXIA TOUR IN INDIA – BANGALORE FINAL.

 Back to Day 1 of the India Chronic Hypoxia tour

Dr. Biramar the Principal and Dean, Prof. Nanjundiaha Shashidhara from the Lead Awareness Program, Prof. Dr. Gustavo Zubieta-Calleja and Prof. B.G. Mulimani, the Vice-Chancellor

India Grand Chronic Hypoxia Tour – Bijapur

Grand Chronic Hypoxia Tour throughout India July 2016 in the city of Bijapur

In this series of consecutive blogs, you can read about this outstanding scientific tour. Each blog is dedicated to one city and one scientific concept presented in the conference “Extraordinary Adaptation to Chronic Hypoxia and Life at High Altitude”.

Back to Day 1 of the India Chronic Hypoxia tour

On the way from Bellary to Bijapur, we visited a temple in honor of, that is located below the water level at the Krishna River.

The entrance to the Temple of Shri Basavechwar Aikyamantap.

The entrance to the Temple of Shri Basavechwar Aikyamantap.

The tomb of Shri Basavechwar Aikyamantap, below the water level !! An extraordinary Hindu thinker.

The tomb of Shri Basavechwar Aikyamantap, below the water level !!
An extraordinary Hindu thinker.

BLDE University Conference

It is hard to explain the fantastic visit to Bijapur. BLDE University is truly a jewel within India, and the presence of Prof. Kusal Das is certainly noteworthy. Prof. B.G. Mulimani, Vice-Chancellor and Chairman, Dr. M.S. Biradar Dean of the Faculty of Medicine and Principal, Dr. J.G. Amber, Registrar and several other professors and Board Members were so kind with us and made our stay a true delight. We truly felt at home at BLDE.

 

Welcome Reception at the International Guest House in BLDE. here with the Vice-Chancellor Prof. B.G. Mulimani

Welcome Reception at the International Guest House in BLDE. here with the Vice-Chancellor Prof. B.G. Mulimani and the Principal & Dean of the Faculty of Medicine Dr. M.S. Biradar.

 

The reception with distinguished faculty  of BLDE. In the center is Prof. Kusal Das ,Right next to him on the right Prof. Thuppil Venkatesh and Prof. Nanjundiaha Shashidhara (at far right)

The reception with distinguished faculty of BLDE. In the center is Prof. Kusal Das ,Right next to him on the right Prof. Thuppil Venkatesh and Prof. Nanjundiaha Shashidhara (at far right)

 

Dr. Biramar the Principal and Dean, Prof. Nanjundiaha Shashidhara from the Lead Awareness Program, Prof. Dr. Gustavo Zubieta-Calleja and Prof. B.G. Mulimani, the Vice-Chancellor

Dr. Biramar the Principal and Dean, Prof. Nanjundiaha Shashidhara from the Lead Awareness Program, Prof. Dr. Gustavo Zubieta-Calleja and Prof. B.G. Mulimani, the Vice-Chancellor

The visit to the 7 ecos Muslim temple Gol Gungbaz. The acoustics are a absolutely formidable. You say something and it will eco back about 7 times!!! Incredible Indian technology from the old times.

The visit to the 7 ecos Muslim temple Gol Gungbaz. The acoustics are a absolutely formidable. You say something and it will eco back about 7 times!!! Incredible Indian technology from the old times.

 

BLDE University Entrance

BLDE University Entrance

Meeting at the Principal and Dean's office Dr. Biramar at BLDE University

Meeting at the Principal and Dean’s office Dr. Biramar at BLDE University

Meeting at Dr. Biramar's office with the presence of the Vice-Chancellor of BLDE University.

Meeting at Dr. Biramar’s office with the presence of the Vice-Chancellor of BLDE University.

BLDE University invitation to the conference of Prof. Dr. Gustavo Zubieta-Calleja of IPPA, Bolivia

BLDE University invitation to the conference of Prof. Dr. Gustavo Zubieta-Calleja of IPPA, Bolivia

Going to visit Prof. Kusal Das's Laboratory.

Going to visit Prof. Kusal Das’s Laboratory.

Prof. Kusal Das' Outstanding Laboratory !!

Prof. Kusal Das’ Outstanding Laboratory !!

 

The head Prof. Kusal Das, researchers and students at the Laboratory of Vascular physiology and Medicine

The head Prof. Kusal Das, researchers and students at the Laboratory of Vascular physiology and Medicine

Prof. Kusal Das, introduces his researchers and students at his Laboratory of Vascular Physiology and Medicine, an elite intelectual group.

Prof. Kusal Das, introduces his researchers and students at his Laboratory of Vascular Physiology and Medicine, an elite intelectual group.

A special moment with Prof. Thuppil Venkatesh and Prof. Kusal Das.

A special moment with Prof. Thuppil Venkatesh and Prof. Kusal Das.

Prof. Kusal Das describing his stroke models to Prof. Dr. Gustavo Zubieta-Calleja at the Laboratory of Vascular Physiology and Medicine.

Prof. Kusal Das describing his stroke models to Prof. Dr. Gustavo Zubieta-Calleja at the Laboratory of Vascular Physiology and Medicine.

Prof. Kusal Das has created the Laboratory of Vascular Physiology and Medicine and is also the Chief editor of the BLDE Journal

At Prof. Kusal Das's Office, in the Laboratory of Vascular Physiology and Medicine of BLDE.

At Prof. Kusal Das’s Office, in the Laboratory of Vascular Physiology and Medicine of BLDE.

 

Prof. Kusal Das, introduces his researchers and students at his Laboratory of Vascular Physiology and Medicine, an elite intelectual group.

Prof. Kusal Das, introduces his researchers and students at his Laboratory of Vascular Physiology and Medicine, an elite intelectual group.

A visit to the Ibrahim Roza, mausoleum complex where Ibrahim Adil Shah II is buried with his queen, Taj Sultana.

A visit to the Ibrahim Roza, mausoleum complex where Ibrahim Adil Shah II is buried with his queen, Taj Sultana.

Invitation to the Conference.

Invitation to the Conference.

 

An interesting visit of the Shri B. M. Partil Medical Colege Hospital followed.

Visiting the Hospital

Visiting the Hospital with the kind guidance of Dr. Santosh Nemegouda, the Pulmonologist.

Before the conference receiving the beautiful bouquet.

Before the conference receiving the beautiful bouquet.

Introduction to the conference with words by the Principal and Dean of BLDE, Dr. Biramar

Introduction to the conference with words by the Principal and Dean of BLDE, Dr. Briar

 

ONE CONCEPT INCLUDED IN THE CONFERENCE “Extraordinary Adaptation to Chronic Hypoxia and Life at High altitude”:

The formula of Adaptation to high altitude. The fundamental variables are time and altitude. The time factor of adaptation to high altitude is trascendental for adaptation, and the hemoglobin increase is considered the optimal adaptation factor. The curves showing the increase and time taken to reach to the optimal hematocrit on an ascent to city like La Paz, between 4100 and 3100m, were shown and analyzed. The hemoglobin increase is the most energy efficient mechanism of adaptation, reducing the extra energetic cost of the cardio-pulmonary system and allowing for the optimal exercise performance at high altitude.

Prof. Dr. Gustavo Zubieta-Calleja, giving his talk and discussing the Tolerance to Hypoxia Formula at BLDE Medical College.

Prof. Dr. Gustavo Zubieta-Calleja, giving his talk and discussing the Tolerance to Hypoxia Formula at BLDE Medical College.

 

Touching the aspect of the two biological pumps of the organism: Pneumodynamic and Hemodynamic.

Touching the aspect of the two biological pumps of the organism: Pneumodynamic and Hemodynamic.

Prof. Thuppil Venkatesh giving his talk about the effect of Lead Toxicity in Children

Prof. Thuppil Venkatesh giving his talk about the effect of Lead Toxicity in Children

Prof. Thuppil Venkatesh “The Lead man of India” has created conscience about lead toxicity throughout India and the Asian region, creating laboratories to test lead levels in blood, in materials, food and also in paints.

Felicitation by the Vice-Chancellor and the Dean and Principal of BLDE Medical College after the conference.

Felicitation by the Vice-Chancellor and the Dean and Principal of BLDE Medical College after the conference.

 

Click here to go to the next days of the GRAND CHRONIC HYPOXIA TOUR IN INDIA- KARAD

 Back to Day 1 of the India Chronic Hypoxia tour